1-(3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3,3-dimethylazetidin-2-one CAS 339100-38-8
| CAS No. | 339100-38-8 |
| Molecular Formula | C17H14ClF3N2O2 |
| Molecular Weight | 370.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 370.75 g/mol gives 1-(3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3,3-dimethylazetidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-(3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3,3-dimethylazetidin-2-one (CAS 339100-38-8), a certified reference material (molecular formula C17H14ClF3N2O2, MW 370.75 g/mol) for analytical method development and quality control.
1-(3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3,3-dimethylazetidin-2-one (C17H14ClF3N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3,3-dimethylazetidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H14ClF3N2O2 |
| Molecular Weight | 370.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- (4S)-6-Chloro-3,4-dihydro-4-hydroxy-3-[(1R)-1-phenylethyl]-4-(trifluoromethyl)-2(1H)quinazolinone (CAS 247565-03-3)
- 1-(3-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}phenyl)-3-(dimethylamino)-2-propen-1-one (CAS 339023-71-1)
- 1-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-3,3-dimethylazetidin-2-one (CAS 341965-76-2)
- 2-Chloro-5-nitro-N-(4-(pyrazin-2-yloxy)phenyl)benzamide (CAS 647853-09-6)
- 2-Chloro-5-nitro-N-(4-(pyrimidin-2-yloxy)phenyl)benzamide (CAS 647853-08-5)
- N-(2-Chloro-5-(trifluoromethyl)phenyl)-6-(pyrrolidin-1-yl)pyridazine-3-carboxamide (CAS 1396790-87-6)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((dimethylamino)methylene)-2-(pyridin-2-yl)acetamide (CAS 338407-48-0)
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Recommended Standards
- (4-Chlorophenyl)(3-morpholino-5-(trifluoromethyl)pyridin-2-yl)methanone (CAS 338959-91-4)
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- 1-Hexadecylzinc bromide (CAS 737797-10-3)
- Quazepam Related Compound A (30 mg) (7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepine-2-one) (CAS 49606-44-2)
- n-(Furan-2-ylmethyl)-2-methylbutan-2-amine (CAS 931992-32-4)
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- N-Methyl-2-phenylcyclopropanamine (CAS 61114-44-1)
- tert-Butyl 3-formyl-6-methoxy-1H-indazole-1-carboxylate (CAS 691900-94-4)
- 7-Bromo-4-fluoro-1H-benzimidazole (CAS 1360968-91-7)
- 2-[(2,4-difluorophenyl)methoxy]benzaldehyde (CAS 632626-21-2)
- 3-Ethoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (CAS 887921-58-6)
- 4-[(ethylsulfanyl)methyl]pyridin-2-amine (CAS 1247197-32-5)
- C-Peptide (Proinsulin) (CAS 59112-80-0)
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