2-((2,5-Dichloro-N-phenylphenyl)sulfonamido)-N,N-dimethylacetamide CAS 339103-10-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((2,5-Dichloro-N-phenylphenyl)sulfonamido)-N,N-dimethylacetamide.

2-((2,5-Dichloro-N-phenylphenyl)sulfonamido)-N,N-dimethylacetamide (CAS 339103-10-5), molecular formula C16H16Cl2N2O3S and molecular weight 387.28 g/mol, is a CATO reference standard with documented purity and traceability.

2-((2,5-Dichloro-N-phenylphenyl)sulfonamido)-N,N-dimethylacetamide (C16H16Cl2N2O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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