2-(3-(((4-Chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-2-methyl-1,3-dioxolane CAS 339276-53-8
| CAS No. | 339276-53-8 |
| Molecular Formula | C17H16ClNO6S |
| Molecular Weight | 397.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(3-(((4-Chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-2-methyl-1,3-dioxolane is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(3-(((4-Chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-2-methyl-1,3-dioxolane (CAS 339276-53-8), a certified reference material (molecular formula C17H16ClNO6S, MW 397.83 g/mol) for analytical method development and quality control.
The molecular framework of 2-(3-(((4-Chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-2-methyl-1,3-dioxolane (C17H16ClNO6S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(3-(((4-Chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-2-methyl-1,3-dioxolane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H16ClNO6S |
| Molecular Weight | 397.83 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 5-((4-Chlorophenyl)sulfonyl)-N-(4-fluorophenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 338791-91-6)
- 3-((3-Chlorophenyl)sulfonyl)-6,7-difluoro-1-propylquinolin-4(1H)-one (CAS 1326860-25-6)
- (E)-[(4-Chlorophenyl)methoxy]({1-[3-(pyrrolidin-1-yl)-5-(trifluoromethyl)pyridin-2-yl]ethylidene})amine (CAS 866145-16-6)
- 2-((2-(4-Chlorophenyl)-6-(2-(hydroxyamino)-2-oxoethyl)pyrimidin-4-yl)amino)benzamide (CAS 57630-88-3)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 303091-54-5)
- 1-(3-Chlorophenyl)-4-(5-(4-methoxyphenethyl)-1,2,4-oxadiazol-3-yl)pyrrolidin-2-one (CAS 1170059-82-1)
- 1-(3-Chlorophenyl)-3-(1-(3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)cyclohexyl)urea (CAS 1396856-26-0)
- 2-(2-Chlorophenyl)-N-{1-[3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl]cyclohexyl}acetamide (CAS 1396860-62-0)
Recommended Standards
- N-(4-(5-chloro-2-methylphenyl)piperazin-1-yl)-N-(3-(trifluoromethyl)phenyl)formamide (CAS 401637-50-1)
- 2-{2-[(1E)-{[(2-chloro-4-fluorophenyl)methoxy]imino}methyl]-1H-pyrrol-1-yl}-4-(dimethylamino)pyridine-3-carbonitrile (CAS 303986-45-0)
- N-(2-chloro-5-(trifluoromethyl)phenyl)-2-(4-phenylpiperazin-1-yl)acetamide (CAS 297150-41-5)
- 2-Chloro-6-ethoxy-4-formylphenyl 4-acetamidobenzenesulfonate (CAS 432012-07-2)
- 2-Bromo-N-(2,3-dimethylphenyl)propanamide (CAS 1119451-12-5)
- 3-(2,6-Difluorophenyl)-4-((3-(trifluoromethyl)phenoxy)methyl)thiazole-2(3H)-thione (CAS 866153-95-9)
- 2-(Aminomethyl)-3-fluoro-4-methoxybenzonitrile (CAS 1913255-87-4)
- 2-Bromo-3-fluorobenzoic Acid (CAS 132715-69-6)
- (2S,4S)-N-Boc-4-hydroxy-3,3-dimethylpyrrolidine-2-carboxylicacid (CAS 174060-99-2)
- 2-Methylpiperidine hydrochloride (CAS 5119-88-0)
- N-(2-Cyano-4-fluoro-phenyl)-methanesulfonamide (CAS 1192348-55-2)
- 5-Bromo-2-chloro-4-methylbenzoic acid (CAS 500579-62-4)
- N-Deethylcyanazine amide (CAS 36556-77-1)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
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