2-[(2-Chlorophenyl)methanesulfonyl]-1-methyl-4,5-diphenyl-1H-imidazole CAS 339277-72-4
| CAS No. | 339277-72-4 |
| Molecular Formula | C23H19ClN2O2S |
| Molecular Weight | 422.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-[(2-Chlorophenyl)methanesulfonyl]-1-methyl-4,5-diphenyl-1H-imidazole (CAS 339277-72-4), a certified reference material (molecular formula C23H19ClN2O2S, MW 422.93 g/mol) for analytical method development and quality control.
The molecular framework of 2-[(2-Chlorophenyl)methanesulfonyl]-1-methyl-4,5-diphenyl-1H-imidazole (C23H19ClN2O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H19ClN2O2S |
| Molecular Weight | 422.93 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 7-(2-Chlorophenyl)-2-(4-phenylpiperazin-1-yl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1242871-68-6)
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- 2-{[(2-chlorophenyl)methyl]sulfanyl}-4-(morpholin-4-yl)-6-phenylpyrimidine-5-carbonitrile (CAS 303985-75-3)
- 4-(2-Chlorophenyl)-N-[4-(dimethylsulfamoyl)phenyl]piperazine-1-carboxamide (CAS 692732-93-7)
- 5-(4-Chlorophenyl)-1-(2,3-dimethylphenyl)-4-(phenylsulfonyl)-1H-pyrazole (CAS 318951-68-7)
- Ethyl 2-(2-{[(4-chlorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)benzenecarboxylate (CAS 250713-81-6)
- 2-[2-(2-Chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-(4-fluorophenyl)acetamide (CAS 338957-29-2)
- 2-[2-(4-Chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-(4-fluorophenyl)acetamide (CAS 338957-19-0)
Recommended Standards
- 2-((4-Chlorobenzyl)sulfonyl)-1-methyl-4,5-diphenyl-1H-imidazole (CAS 339277-07-5)
- 3-(4-Chloro-2-methylphenyl)-2-(((2-methoxyphenyl)thio)methyl)quinazolin-4(3H)-one (CAS 338965-66-5)
- Tianeptine Metabolite MC5 Methyl Ester (CAS 1159977-59-9)
- 4-Chloro-n-(4-ethoxyphenyl)-n-[2-oxo-2-(pyrrolidin-1-yl)ethyl]benzene-1-sulfonamide (CAS 332355-39-2)
- DL-Selenomethionine (CAS 1464-42-2)
- rel-(4aR,7aR)-4-(3-Methylbenzyl)hexahydropyrrolo[3,4-b][1,4]oxazin-3(2H)-one (CAS 1422142-18-4)
- (3-Methylpiperazin-1-yl)(p-tolyl)methanone hydrochloride (CAS 1595144-88-9)
- (3-Fluoro-2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanamine hydrochloride (CAS 2660137-03-9)
- 2-(2,6-Dioxopiperidin-3-yl)-5,7-dihydrocyclopenta[f]isoindole-1,3,6(2H)-trione (CAS 2616551-00-7)
- 4-(Ethylsulfonamido)benzoic acid (CAS 116855-56-2)
- 1,2-Dichloro-5-difluoromethoxy-3-fluorobenzene (CAS 1806353-47-8)
- 2-(propan-2-yl)-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine (CAS 1354963-17-9)
- (4-(Azetidin-1-ylmethyl)phenyl)(4-bromo-2-fluorophenyl)methanone (CAS 898756-87-1)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
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