2-(4-(Trifluoromethyl)phenyl)nicotinic acid CAS 339538-65-7
| CAS No. | 339538-65-7 |
| Molecular Formula | C13H8F3NO2 |
| Molecular Weight | 267.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-(Trifluoromethyl)phenyl)nicotinic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(4-(Trifluoromethyl)phenyl)nicotinic acid (CAS 339538-65-7), a certified reference material (molecular formula C13H8F3NO2, MW 267.20 g/mol) for analytical method development and quality control.
Based on its molecular formula C13H8F3NO2, 2-(4-(Trifluoromethyl)phenyl)nicotinic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 267.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(4-(Trifluoromethyl)phenyl)nicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H8F3NO2 |
| Molecular Weight | 267.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 4-((5-(Trifluoromethyl)pyridin-2-yl)oxy)benzaldehyde (CAS 103962-21-6)
- 4-((3-(Trifluoromethyl)pyridin-2-yl)oxy)benzaldehyde (CAS 1086379-05-6)
- 4-((6-(Trifluoromethyl)pyridin-2-yl)oxy)benzaldehyde (CAS 1086379-09-0)
- 5-Phenyl-3-(trifluoromethyl)-2-pyridinecarboxylic acid (CAS 1211578-17-4)
- 3-Phenyl-6-(trifluoromethyl)-2-pyridinecarboxylic acid (CAS 1214381-18-6)
- 3-Phenyl-5-(trifluoromethyl)picolinic acid (CAS 1214390-26-7)
- 2-(4-(Trifluoromethyl)phenyl)isonicotinic acid (CAS 1225900-99-1)
- 2-(2-(Trifluoromethyl)phenyl)nicotinic acid (CAS 1225923-56-7)
Recommended Standards
- 2-(3-(Trifluoromethyl)phenyl)nicotinic acid (CAS 635325-17-6)
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- 2-Bromo-3-(2,3,4,5,6-pentamethylphenyl)-1-propene (CAS 951893-58-6)
- 3,4-Dichlorotetrahydrothiophene 1,1-dioxide (CAS 3001-57-8)
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