2-(Chloromethyl)-3-fluoroanisole CAS 339586-05-9
| CAS No. | 339586-05-9 |
| Molecular Formula | C8H8ClFO |
| Molecular Weight | 174.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Chloromethyl)-3-fluoroanisole (C8H8ClFO) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(Chloromethyl)-3-fluoroanisole (CAS 339586-05-9), molecular formula C8H8ClFO and molecular weight 174.60 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8ClFO |
| Molecular Weight | 174.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chloromethyl Standards
- 2-(Chloromethyl)-1-fluoro-4-methoxybenzene (CAS 1076197-70-0)
- 1-(Chloromethyl)-3-fluoro-5-methoxybenzene (CAS 1214346-07-2)
- 1-(Chloromethyl)-2-fluoro-3-methoxybenzene (CAS 178974-63-5)
- 2-(chloromethyl)-4-fluoro-1-methoxybenzene (CAS 19415-40-8)
- [2-(Chloromethyl)-5-Fluorophenyl]Methanol (CAS 313232-91-6)
- 1-(Chloromethyl)-3-fluoro-2-methoxybenzene (CAS 303043-93-8)
- 4-(Chloromethyl)-1-fluoro-2-methoxybenzene (CAS 276861-59-7)
- 4-(Chloromethyl)-2-fluoro-1-methoxybenzene (CAS 351-52-0)
Recommended Standards
- 2-(4-Chloro-3-fluorophenyl)ethanol (CAS 206362-79-0)
- 2-Chloro-1-ethoxy-3-fluorobenzene (CAS 909122-13-0)
- 2-(4-Chloro-2-fluorophenyl)ethanol (CAS 667461-51-0)
- 2-Chloro-4-ethoxy-1-fluorobenzene (CAS 289039-45-8)
- N1-methyl-N1-(pyridin-4-ylmethyl)ethane-1,2-diamine (CAS 933717-41-0)
- 4,4A-dihydrodibenzo[b,f]oxepine-1,3-diamine dihydrochloride (CAS 1051369-20-0)
- N-(3-Methoxyphenyl)-2-(quinolin-2-ylthio)acetamide (CAS 670273-97-9)
- N-(1,3-Diphenyl-1H-pyrazol-5-yl)benzamide (CAS 77746-90-8)
- 3-Chloro-4-(3-(4-chlorophenyl)-5-oxoimidazolidin-1-yl)benzenesulfonamide (CAS 53298-04-7)
- 1-Methyl-1H-pyrazolo[3,4-d]pyridazin-4(5H)-one (CAS 40995-46-8)
- 5-Isobutyl-1,2,4-oxadiazol-3-amine (CAS 868696-43-9)
- 2-(Methylthio)thieno[2,3-d]pyrimidin-4(1H)-one (CAS 309976-36-1)
- 4-(Benzo[d][1,3]dioxol-5-yl)-2-((3-methoxybenzyl)thio)-1,4-dihydro-5H-indeno[1,2-d]pyrimidin-5-one (CAS 861211-19-0)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
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