N-(2,5-dioxotetrahydrofuran-3-yl)acetamide CAS 3397-54-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(2,5-dioxotetrahydrofuran-3-yl)acetamide.

CATO supplies N-(2,5-dioxotetrahydrofuran-3-yl)acetamide (CAS 3397-54-4), a certified reference material (molecular formula C6H7NO4, MW 157.12 g/mol) for analytical method development and quality control.

The molecular framework of N-(2,5-dioxotetrahydrofuran-3-yl)acetamide (C6H7NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(2,5-dioxotetrahydrofuran-3-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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