1-Oxo-1,2-dihydroisoquinoline-4-carboxylic acid CAS 34014-51-2

Purity 97%+In StockPharmaceutical Standards
CAS No.34014-51-2
Molecular FormulaC10H7NO3
Molecular Weight189.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Oxo-1,2-dihydroisoquinoline-4-carboxylic acid CAS 34014-51-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 189.17 g/mol gives 1-Oxo-1,2-dihydroisoquinoline-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-Oxo-1,2-dihydroisoquinoline-4-carboxylic acid (CAS 34014-51-2), molecular formula C10H7NO3 and molecular weight 189.17 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-Oxo-1,2-dihydroisoquinoline-4-carboxylic acid (C10H7NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H7NO3
Molecular Weight189.17 g/mol
AppearancePale yellow to yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1966
Nitrogen Atoms1

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