2-((2-(4-Methylpiperazin-1-yl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile CAS 340816-86-6
| CAS No. | 340816-86-6 |
| Molecular Formula | C17H18N4OS2 |
| Molecular Weight | 358.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((2-(4-Methylpiperazin-1-yl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-((2-(4-Methylpiperazin-1-yl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile (CAS 340816-86-6), molecular formula C17H18N4OS2 and molecular weight 358.48 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-((2-(4-Methylpiperazin-1-yl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile (C17H18N4OS2) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-((2-(4-Methylpiperazin-1-yl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H18N4OS2 |
| Molecular Weight | 358.48 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Methylpiperazin Standards
- 3-(4-Methylpiperazin-1-yl)-1-(4-morpholinophenyl)pyrrolidine-2,5-dione (CAS 302552-63-2)
- 2-(4-Methylpiperazin-1-yl)-n-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 1480399-95-8)
- 3-(4-Methylpiperazin-1-yl)-1-(4-(piperidin-1-yl)phenyl)pyrrolidine-2,5-dione (CAS 301313-30-4)
- 4-{[4-Methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]amino}-4-oxobutanoic acid (CAS 1119449-97-6)
- 4-(4-Methylpiperazin-1-yl)-6-phenyl-2-(pyridin-2-yl)pyrimidine-5-carbonitrile (CAS 320418-22-2)
- 5-[4-(4-Methylpiperazin-1-yl)phenyl]-N-phenyl-1H-pyrazole-1-carboxamide (CAS 321998-95-2)
- 4-Methyl-11-(4-methylpiperazin-1-yl)-8-thia-12-azatetracyclo[8.8.0.0^{2,7}.0^{13,18}]octadeca-1(18),2,4,6,10,12,14,16-octaene (CAS 866136-53-0)
- 898762-15-7 {2-[(4-Methylpiperazin-1-yl)methyl]phenyl}[4-(trifluoromethyl)phenyl]methanone DTXSID90643889 (CAS 898762-15-7)
Recommended Standards
- 1,3-Dibenzyl-2-(4-methoxyphenyl)imidazolidine (CAS 307338-62-1)
- 2-((4-Ethyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(m-tolyl)acetamide (CAS 557072-68-1)
- 1,2,3,5,6,7,8,9-Octahydro-3-(3-methoxyphenyl)-2-thioxo-4H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-one (CAS 519150-62-0)
- 2-(1-(Benzylsulfonyl)pyrrolidin-2-yl)benzo[d]thiazole (CAS 672925-47-2)
- 6-Dodecylquinolin-8-ol (CAS 52667-16-0)
- 4-Bromo-2-methylpyrazolo[1,5-a]pyridine (CAS 2857113-38-1)
- 2'-(Hydroxymethyl)-[1,1'-biphenyl]-2-carbaldehyde (CAS 14665-22-6)
- 3,6-dibromopyrazolo[1,5-a]pyrimidine (CAS 55405-68-0)
- Rubber Oligomer 10 (CAS CATO-C3D-5837)
- 3-Phosphonobenzenesulfonic acid (CAS 126180-64-1)
- Ethyl 3-[(E)-[(dimethylamino)methylidene]amino]-4-methoxythieno[2,3-b]pyridine-2-carboxylate (CAS 341966-55-0)
- 3-(4-methyl-1,3-thiazol-2-yl)propanoic acid (CAS 89776-65-8)
- 1-((3-Hydroxypropyl)thio)-3-phenylpropan-2-one (CAS 1480315-35-2)
- Semaglutide impurity 203 (CAS CATO-C4X-2226203)
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