2-Methylimidazo[1,2-a]pyridin-3-amine hydrochloride CAS 34164-99-3
| CAS No. | 34164-99-3 |
| Molecular Formula | C8H9N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Methylimidazo[1,2-a]pyridin-3-amine hydrochloride (CAS 34164-99-3) is a high-purity analytical reference standard with the molecular formula C8H9N3HCl and a molecular weight of 183.64 g/mol.
2-Methylimidazo[1,2-a]pyridin-3-amine hydrochloride (C8H9N3HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9N3 HCl |
| Molecular Weight | 183.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Methylimidazo Standards
- 2-Methylimidazo[1,2-a]pyridin-6-ol (CAS 1001434-68-9)
- 2-Methylimidazo[1,2-a]pyridin-7-ol (CAS 1001434-77-0)
- 3-Methylimidazo[1,2-a]pyridine-2-carbaldehyde (CAS 1001754-85-3)
- 1-(2-Methylimidazo[1,2-a]pyrimidin-3-yl)ethanone (CAS 100289-21-2)
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- 3-methylimidazo[2,1-b]thiazole-5-carboxylic acid (CAS 1007874-80-7)
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Recommended Standards
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