Methylene blue Impurity 3 CAS 34185-21-2
| CAS No. | 34185-21-2 |
| Molecular Formula | C14H14N3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Methylene blue Impurity 3 (C14H14N3SCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Methylene blue Impurity 3 (CAS 34185-21-2), a pharmacopoeial impurity reference standard (molecular formula C14H14N3SCl, MW 291.80 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Methylene blue Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14N3S Cl |
| Molecular Weight | 291.80 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methylene Standards
- γ-Methylene-γ-butyrolactone (CAS 10008-73-8)
- 4,4＇-Methylene-Bis(2-chloroaniline) (CAS 101-14-4)
- 5-Methylene-2-phenyl-1,3-dioxolan-4-one (CAS 101822-11-1)
- 2-Methylene-1,3,6-trioxocane (CAS 105649-50-1)
- 6-Methyl-3-methylene-3,4-dihydroquinoxalin-2(1H)-one (CAS 106480-88-0)
- 5-Methylene-2(5H)-furanone (CAS 108-28-1)
- 3-(2-Methylene-4-phenylbutanoyl)oxazol-2(3H)-one (CAS 1151767-07-5)
- (Methylene-d2)gibberellin A5 (CAS 120396-32-9)
Recommended Standards
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- 2-[(2-Methyl-3-nitroanilino)carbonyl]cyclohexanecarboxylic acid (CAS 496039-60-2)
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- (E)-{1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene}amino N-cyclohexylcarbamate (CAS 477872-49-4)
- 4-(Trifluoromethyl)picolinaldehyde (CAS 132470-83-8)
- Vitamin D3 β-D-Glucuronide, >90% (CAS 57918-08-8)
- 4-Chloro-6-(p-tolyl)thieno[2,3-d]pyrimidine (CAS 1610772-26-3)
- Characteristic MSH-Tetrapeptide (CAS 4289-02-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com