4-[(E)-2-[(4-Methylphenyl)methylidene]hydrazin-1-yl]-2-(trifluoromethyl)quinazoline CAS 341964-20-3
| CAS No. | 341964-20-3 |
| Molecular Formula | C17H13F3N4 |
| Molecular Weight | 330.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-[(E)-2-[(4-Methylphenyl)methylidene]hydrazin-1-yl]-2-(trifluoromethyl)quinazoline.
4-[(E)-2-[(4-Methylphenyl)methylidene]hydrazin-1-yl]-2-(trifluoromethyl)quinazoline (CAS 341964-20-3) is a high-purity analytical reference standard with the molecular formula C17H13F3N4 and a molecular weight of 330.31 g/mol.
The molecular framework of 4-[(E)-2-[(4-Methylphenyl)methylidene]hydrazin-1-yl]-2-(trifluoromethyl)quinazoline (C17H13F3N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-[(E)-2-[(4-Methylphenyl)methylidene]hydrazin-1-yl]-2-(trifluoromethyl)quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H13F3N4 |
| Molecular Weight | 330.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related E Standards
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- 7-benzyl-2-(4-methylphenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one (CAS 1031990-66-5)
- 5-{1-[(4-methylphenyl)methyl]-1H-pyrazol-3-yl}-2-phenyl-1,3-thiazole (CAS 318255-92-4)
- 4-Methyl-3-{3-[(4-methylphenyl)methoxy]thiophen-2-yl}-5-(methylsulfanyl)-4H-1,2,4-triazole (CAS 343375-90-6)
- 2-{[(4-methylphenyl)methyl]sulfanyl}-5-[2-(methylsulfanyl)phenyl]-1,3,4-oxadiazole (CAS 339015-38-2)
- 3-(3-Methylphenyl)-2-sulfanyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3h)-one (CAS 341499-06-7)
Recommended Standards
- 4,4,5,5-Tetramethyl-2-(2,4,6-triisopropylphenyl)-1,3,2-dioxaborolane (CAS 914675-53-9)
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- 3-(Benzenesulfonyl)-2-oxo-2H-chromene-6-carboxylic acid (CAS 895651-88-4)
- 6-(2-Fluorophenyl)-2-(4-(2-hydroxyethyl)-3-methyl-5-oxo-2,5-dihydro-1H-pyrazol-1-yl)pyrimidin-4(3H)-one (CAS 866138-08-1)
- N-(2-(1H-indol-3-yl)ethyl)-4-chloro-3-nitrobenzenesulfonamide (CAS 880139-18-4)
- 4-(PRopan-2-yloxy)-2-(trifluoromethyl)phenol (CAS 1243404-94-5)
- Regorafenib Impurity 45 (CAS 39893-50-0)
- 2-Methyl-d3-propionitrile-3,3,3-d3 (CAS 174736-88-0)
- Niobium carbide (CAS 12069-94-2)
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- 3-Amino-4-phenylisoxazol-5-ol (CAS 748157-17-7)
- 1-Benzylpiperidine-4-thiol (CAS 139362-30-4)
- N'-(3,5-Dimethyl-4,5-dihydroisoxazol-5-yl)propionohydrazide (CAS 325490-38-8)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
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