(2Z)-2-{[2-(trifluoromethyl)phenyl]methylidene}-1-azabicyclo[2.2.2]octan-3-one CAS 341965-87-5
| CAS No. | 341965-87-5 |
| Molecular Formula | C15H14F3NO |
| Molecular Weight | 281.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2Z)-2-{[2-(trifluoromethyl)phenyl]methylidene}-1-azabicyclo[2.2.2]octan-3-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2Z)-2-{[2-(trifluoromethyl)phenyl]methylidene}-1-azabicyclo[2.2.2]octan-3-one (CAS 341965-87-5), molecular formula C15H14F3NO and molecular weight 281.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2Z)-2-{[2-(trifluoromethyl)phenyl]methylidene}-1-azabicyclo[2.2.2]octan-3-one (C15H14F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2Z)-2-{[2-(trifluoromethyl)phenyl]methylidene}-1-azabicyclo[2.2.2]octan-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H14F3NO |
| Molecular Weight | 281.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Z Standards
- N-((5-(2-(Trifluoromethyl)phenyl)furan-2-yl)methyl)cyclopropanamine (CAS 1155138-47-8)
- (2Z)-2-{[3-(trifluoromethyl)phenyl]methylidene}-1-azabicyclo[2.2.2]octan-3-one (CAS 866050-94-4)
- (2Z)-2-{[4-(trifluoromethyl)phenyl]methylidene}-1-azabicyclo[2.2.2]octan-3-one (CAS 52407-95-1)
- 1-(4-(Trifluoromethyl)phenyl)-4,5,6,7-tetrahydro-1H-indazol-4-amine (CAS 1203661-52-2)
- 1-(3-(Trifluoromethyl)phenyl)-4,5,6,7-tetrahydro-1H-indazol-4-amine (CAS 1203661-53-3)
- 2-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]aniline (CAS 937607-82-4)
- 4-(3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1h-indazol-1-yl)aniline (CAS 353457-63-3)
- 4-(Trifluoromethyl)-1,2-dihydro-6-(pyridin-3-yl)-2-thioxopyridine-3-carbonitrile (CAS 893752-69-7)
Recommended Standards
- (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(1-hydroxyethyl)tetrahydrofuran-3,4-diol (CAS 847659-02-3)
- (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-((S)-1-hydroxyethyl)tetrahydrofuran-3,4-diol (CAS 35868-16-7)
- (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-((R)-1-hydroxyethyl)tetrahydrofuran-3,4-diol (CAS 3253-81-4)
- (3-Nitro-5-(quinoxalin-2-yl)phenyl)methanol (CAS 2098062-41-8)
- 2-Ethyl-7-phenyl-1H-indene (CAS 154380-63-9)
- 4-Ethyl-5-(4-ethyl-5-methylthiophen-3-yl)-4H-1,2,4-triazole-3-thiol (CAS 438228-34-3)
- 2-Amino-N-(2-oxopiperidin-3-yl)benzamide hydrochloride (CAS 1826099-06-2)
- 1-(4-(Trifluoromethyl)phenyl)-1H-pyrrole (CAS 92636-38-9)
- 2-(3,4-Dimethyl-2,5-dioxopyrrolidin-1-yl)acetic acid (CAS 1507487-02-6)
- (S)-5-(((tert-Butyldimethylsilyl)oxy)methyl)-1-(2-hydroxyethyl)pyrrolidin-2-one (CAS 2377182-42-6)
- N-Ethyl-N-pyrrolidin-2-ylmethyl-acetamide (CAS 1353979-56-2)
- (2-Methoxycyclohexyl)methanamine (CAS 1155125-80-6)
- 4-(4-Methoxyphenyl)-5-phenyl-4h-1,2,4-triazol-3-yl hydrosulfide (CAS 63279-75-4)
- ([13C6]Leu14)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802078-39-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com