1-[(2,4-Dichlorophenyl)methyl]-3-[(4-methylphenyl)methyl]imidazolidine-2,4,5-trione CAS 341966-53-8
| CAS No. | 341966-53-8 |
| Molecular Formula | C18H14Cl2N2O3 |
| Molecular Weight | 377.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[(2,4-Dichlorophenyl)methyl]-3-[(4-methylphenyl)methyl]imidazolidine-2,4,5-trione.
CATO supplies 1-[(2,4-Dichlorophenyl)methyl]-3-[(4-methylphenyl)methyl]imidazolidine-2,4,5-trione (CAS 341966-53-8), a certified reference material (molecular formula C18H14Cl2N2O3, MW 377.22 g/mol) for analytical method development and quality control.
The molecular framework of 1-[(2,4-Dichlorophenyl)methyl]-3-[(4-methylphenyl)methyl]imidazolidine-2,4,5-trione (C18H14Cl2N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-[(2,4-Dichlorophenyl)methyl]-3-[(4-methylphenyl)methyl]imidazolidine-2,4,5-trione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14Cl2N2O3 |
| Molecular Weight | 377.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorophenyl Standards
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- 1-(3,5-Dichlorophenyl)-N-(4-methoxyphenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 338408-57-4)
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- 1-(2,5-Dichlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one (CAS 312621-02-6)
- 4-[(2Z)-3-(2,4-Dichlorophenyl)prop-2-enoyl]phenyl 2,2-dimethylpropanoate (CAS 298215-30-2)
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Recommended Standards
- 1,2-Bis(4-chloro-2-nitrophenyl)disulfane (CAS 2050-66-0)
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- 1,2-Bis(2-chloro-5-nitrophenyl)disulfane (CAS 20201-05-2)
- N-(4-Bromophenyl)-5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine (CAS 827580-67-6)
- 4-Cyclopentyl-5-isopropyl-4h-1,2,4-triazole-3-thiol (CAS 1038384-69-8)
- rac Enterolactone -13C3 (CAS 918502-72-4)
- 2-(Benzylsulfanyl)-1,1-bis(4-chlorophenyl)ethan-1-ol (CAS 252026-63-4)
- 4-Cyano-3-cyclopropoxypyridine-2-sulfonamide (CAS 1243450-84-1)
- 3-((1R,2R,4S)-2-Hydroxy-4-(hydroxymethyl)cyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7(4H)-one (CAS 50767-25-4)
- Trans-2-((2-methylfuran-3-yl)thio)cyclohexanol (CAS 61295-48-5)
- (4-Bromophenyl)[4-(trifluoromethyl)phenyl]methanone (CAS 21084-23-1)
- Magnesium 3-hydroxybutanoate (CAS 163452-00-4)
- 4-(Azetidin-3-yl)aniline (CAS 7215-04-5)
- D-[His]1-Semaglutide (CAS CATO-C4X-222652)
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