2-((3,5-Dichlorophenyl)amino)-4-methoxynicotinonitrile CAS 341966-81-2
| CAS No. | 341966-81-2 |
| Molecular Formula | C13H9Cl2N3O |
| Molecular Weight | 294.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((3,5-Dichlorophenyl)amino)-4-methoxynicotinonitrile.
CATO supplies 2-((3,5-Dichlorophenyl)amino)-4-methoxynicotinonitrile (CAS 341966-81-2), a certified reference material (molecular formula C13H9Cl2N3O, MW 294.14 g/mol) for analytical method development and quality control.
The molecular framework of 2-((3,5-Dichlorophenyl)amino)-4-methoxynicotinonitrile (C13H9Cl2N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H9Cl2N3O |
| Molecular Weight | 294.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichlorophenyl Standards
- (6-(2,4-Dichlorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methanamine (CAS 1706461-20-2)
- 2-(2,4-Dichlorophenyl)-1-methoxy-1H-imidazo[4,5-b]pyridine (CAS 338978-54-4)
- 2-[(3,4-Dichlorophenyl)amino]-4-methoxypyridine-3-carbonitrile (CAS 341967-11-1)
- N-(3,4-Dichlorophenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 869072-81-1)
- (2-(3,4-Dichlorophenyl)benzo[d]oxazol-5-yl)methanol (CAS 1494364-81-6)
- 1-(2,6-Dichlorophenyl)-1,3-dihydro-5-hydroxy-2H-indol-2-one (CAS 30267-40-4)
- 2-((2-((2,4-Dichlorophenyl)amino)-2-oxoethyl)thio)acetic acid (CAS 338409-76-0)
- 2-((2-((2,6-Dichlorophenyl)amino)-2-oxoethyl)thio)acetic acid (CAS 338421-32-2)
Recommended Standards
- 2-(((4-Bromophenyl)amino)methylene)cyclohexane-1,3-dione (CAS 341968-26-1)
- 1-[2-(4-bromophenoxy)ethyl]-1,2-dihydropyridin-2-one (CAS 489443-66-5)
- 2-(4-(3,3-Difluorocyclobutyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2361225-63-8)
- 1-(4-Bromophenyl)-2,5-dimethyl-1h-pyrrole-3-carboxylic acid (CAS 694465-29-7)
- N-(2,4-dimethoxybenzyl)-1-(4-methoxyphenyl)methanamine (CAS 510723-61-2)
- (1R,2S)-2-(2,5-dimethylbenzoyl)cyclohexane-1-carboxylic acid (CAS 85603-45-8)
- 3-(2,6-Dimethylphenyl)-1-phenylpropan-1-one (CAS 898754-24-0)
- 2-Methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid (CAS 1060806-08-7)
- Methyl 2-azaspiro[4.4]nonane-3-carboxylate hydrochloride (CAS 1822446-57-0)
- [3-(1,1-Difluoroethyl)oxetan-3-yl]methanol (CAS 2102412-02-0)
- 4-(4-Methoxyphenyl)dihydro-2h-pyran-2,6(3h)-dione (CAS 57171-24-1)
- Methyl phytanate (CAS 1118-77-0)
- N-(2-((6-Phenylthieno[2,3-d]pyrimidin-4-yl)amino)ethyl)acetamide (CAS 924371-24-4)
- [D-His]-Semaglutide B (x TFA Salt) (CAS CATO-C4X-2226117)
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