3,3-Bis(4-fluorophenyl)propanoic acid CAS 342-75-6
| CAS No. | 342-75-6 |
| Molecular Formula | C15H12F2O2 |
| Molecular Weight | 262.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 262.25 g/mol gives 3,3-Bis(4-fluorophenyl)propanoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3,3-Bis(4-fluorophenyl)propanoic acid (CAS 342-75-6) is a high-purity analytical reference standard with the molecular formula C15H12F2O2 and a molecular weight of 262.25 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, 3,3-Bis(4-fluorophenyl)propanoic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 262.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3,3-Bis(4-fluorophenyl)propanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H12F2O2 |
| Molecular Weight | 262.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Bis Standards
- 2,3-Bis(4-fluorophenyl)propanoic acid (CAS 1017324-10-5)
- (2R)-3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic Acid (CAS 890658-79-4)
- 2-[3-(4-Fluorophenyl)-6-oxo-1,6-dihydropyridazin-1-yl]propanoic acid (CAS 1017168-40-9)
- 6-(3-Fluorophenyl)imidazo[2,1-b]thiazole-3-carboxylic acid (CAS 1119452-29-7)
- Ethyl 1-(4-fluorophenyl)-4-formyl-1H-pyrazole-3-carboxylate (CAS 1159691-42-5)
- Ethyl 1-(2-fluorophenyl)-4-formyl-1H-pyrazole-3-carboxylate (CAS 1307314-49-3)
- 1-(3-Fluorophenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 1416342-35-2)
- 1-(2-Fluorophenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 1416345-80-6)
Recommended Standards
- 2,6-Difluoro-4-(5-propylpyrimidin-2-yl)benzaldehyde (CAS 574705-83-2)
- 3,5-Difluoro-4-ethoxybenzophenone (CAS 951884-68-7)
- 2-(3,4-Difluorophenyl)-1-(4-methoxyphenyl)ethan-1-one (CAS 221179-71-1)
- 5-(3-Nitroimidazo[1,2-a]pyridin-2-yl)-1,3,4-thiadiazol-2-amine (CAS 62195-13-5)
- N-(2-(1-Methyl-4-(thiophen-2-yl)-1H-imidazol-2-yl)ethyl)-3-(phenylthio)propanamide (CAS 1396814-80-4)
- 2-((((7,8-Dimethyl-2-oxo-2H-chromen-4-yl)methyl)(ethyl)amino)methyl)-6,7-dimethoxyquinazolin-4(3H)-one (CAS 854131-39-8)
- 5-(4-((tert-Butoxycarbonyl)amino)phenyl)nicotinic acid (CAS 1261892-53-8)
- 3-Bromo-8-phenylimidazo[1,2-a]pyridine (CAS 104271-47-8)
- 4,4,5,5-Tetramethyl-2-(4-((4-(trifluoromethyl)benzyl)oxy)phenyl)-1,3,2-dioxaborolane (CAS 1813554-40-3)
- 4-Bromo-N-(2-chlorobenzyl)-1h-pyrrole-2-carboxamide (CAS 931075-50-2)
- 1-(4-Butoxybenzyl)piperazine (CAS 21867-73-2)
- 4-Amino-N,N-dimethylpiperidine-1-carboxamide (CAS 412356-47-9)
- N-BENZO(G)QUINOLIN-4-YL-N',N'-DIETHYL-ETHANE-1,2-DIAMINE,2 H3PO4 (CAS 56548-50-6)
- Neuropeptide S (rat) (CAS 412938-75-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com