(5-fluoro-2-hydroxyphenyl)(m-tolyl)methanone CAS 3421-8-7

Purity 97%+In StockPharmaceutical Standards
CAS No.3421-8-7
Molecular FormulaC14H11FO2
Molecular Weight230.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(5-fluoro-2-hydroxyphenyl)(m-tolyl)methanone CAS 3421-8-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 230.23 g/mol gives (5-fluoro-2-hydroxyphenyl)(m-tolyl)methanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(5-fluoro-2-hydroxyphenyl)(m-tolyl)methanone (CAS 3421-8-7), molecular formula C14H11FO2 and molecular weight 230.23 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (5-fluoro-2-hydroxyphenyl)(m-tolyl)methanone (C14H11FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (5-fluoro-2-hydroxyphenyl)(m-tolyl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H11FO2
Molecular Weight230.23 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF-containing

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