1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile CAS 342643-23-6
| CAS No. | 342643-23-6 |
| Molecular Formula | C9H7N3 |
| Molecular Weight | 157.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile.
CATO supplies 1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile (CAS 342643-23-6), a certified reference material (molecular formula C9H7N3, MW 157.17 g/mol) for analytical method development and quality control.
Structurally, 1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile (C9H7N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 157.17 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H7N3 |
| Molecular Weight | 157.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Recommended Standards
- 1-Methyl-1H-indazole-7-carbonitrile (CAS 256228-68-9)
- 1-Methyl-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS 914637-99-3)
- 1-Methyl-1H-benzo[d]imidazole-6-carbonitrile (CAS 53484-14-3)
- 1-Methyl-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile (CAS 2121702-71-2)
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