(1-(Thiophen-2-ylsulfonyl)piperidin-4-yl)(3-(trifluoromethyl)piperidin-1-yl)methanone CAS 342779-33-3
| CAS No. | 342779-33-3 |
| Molecular Formula | C16H21F3N2O3S2 |
| Molecular Weight | 410.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (1-(Thiophen-2-ylsulfonyl)piperidin-4-yl)(3-(trifluoromethyl)piperidin-1-yl)methanone.
CATO supplies (1-(Thiophen-2-ylsulfonyl)piperidin-4-yl)(3-(trifluoromethyl)piperidin-1-yl)methanone (CAS 342779-33-3), a certified reference material (molecular formula C16H21F3N2O3S2, MW 410.47 g/mol) for analytical method development and quality control.
The molecular framework of (1-(Thiophen-2-ylsulfonyl)piperidin-4-yl)(3-(trifluoromethyl)piperidin-1-yl)methanone (C16H21F3N2O3S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (1-(Thiophen-2-ylsulfonyl)piperidin-4-yl)(3-(trifluoromethyl)piperidin-1-yl)methanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H21F3N2O3S2 |
| Molecular Weight | 410.47 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Thiophen Standards
- Ethyl 3-(thiophen-2-yl)-5-{[3-(trifluoromethyl)phenyl]sulfanyl}-1,2,4-triazine-6-carboxylate (CAS 338965-93-8)
- 2-(1-Phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl)-3-((tetrahydrofuran-2-yl)methyl)thiazolidin-4-one (CAS 380471-87-4)
- 4-[(E)-[(Thiophen-2-yl)methylidene]amino]phenyl 2,5-dichlorobenzene-1-sulfonate (CAS 329778-39-4)
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Recommended Standards
- UCB-9608, >98% (HPLC) (CAS 1616413-96-7)
- 1-Ethyl-2-imino-10-methyl-N-(2-morpholinoethyl)-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide (CAS 618077-84-2)
- (4R,4′R,4′′R,4′′′R)-2,2′,2′′,2′′′-(1,2,4,5-Benzenetetrayl)tetrakis[4,5-dihydro-4-methyloxazole] (CAS 1613029-64-3)
- 2-{2-[4-(2,6-dimethylphenyl)piperazin-1-yl]ethyl}-7-nitro-3,4-dihydro-2H-1,4-benzoxazin-3-one (CAS 866039-67-0)
- 3,4-Diiodo-1H-pyrazole (CAS 6645-70-1)
- 4-Ethylbenzamide (CAS 33695-58-8)
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- 2-Chloro-4-(4-hydroxyphenyl)nicotinonitrile (CAS 1266160-92-2)
- 4-((2-Chloro-5-nitrobenzylidene)amino)-3-(2-methoxyphenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478257-54-4)
- (5-(4-Chlorophenyl)isoxazol-3-yl)methanamine hydrochloride (CAS 1323699-63-3)
- Methyl 4-chloro-6-methoxypicolinate (CAS 204378-37-0)
- 2,2-difluoro-2-(1-methyl-1H-1,3-benzodiazol-2-yl)acetic acid (CAS 80944-03-2)
- 2-[(2,6-Dichlorobenzyl)oxy]-3-methoxy-benzoyl chloride (CAS 1160251-01-3)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
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