3-(2,2,2-Trifluoroethoxy)picolinonitrile CAS 342816-08-4

Purity 97%+In StockPharmaceutical Standards
CAS No.342816-08-4
Molecular FormulaC8H5F3N2O
Molecular Weight202.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(2,2,2-Trifluoroethoxy)picolinonitrile CAS 342816-08-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 202.13 g/mol gives 3-(2,2,2-Trifluoroethoxy)picolinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-(2,2,2-Trifluoroethoxy)picolinonitrile (CAS 342816-08-4) is a high-purity analytical reference standard with the molecular formula C8H5F3N2O and a molecular weight of 202.13 g/mol.

Based on its molecular formula C8H5F3N2O, 3-(2,2,2-Trifluoroethoxy)picolinonitrile contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 202.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H5F3N2O
Molecular Weight202.13 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2

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