1-bromo-3-fluoro-naphthalene CAS 343-53-3
| CAS No. | 343-53-3 |
| Molecular Formula | C10H16BrF |
| Molecular Weight | 235.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-bromo-3-fluoro-naphthalene is closely related to fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-bromo-3-fluoro-naphthalene (CAS 343-53-3), molecular formula C10H16BrF and molecular weight 235.14 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to fluorine/bromine substitution, 1-bromo-3-fluoro-naphthalene is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 235.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-bromo-3-fluoro-naphthalene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H16BrF |
| Molecular Weight | 235.14 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
Related bromo Standards
- 4-Bromo-2-(propoxymethyl)thiophene (CAS 1065184-25-9)
- 1-bromo-8-fluoro-naphthalene (CAS 33718-15-9)
- 4-Bromo-5-(tert-butyl)thiazol-2-amine (CAS 2738982-10-8)
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- 1-Bromo-4-fluoronaphthalene 21-Acetoxy-9-fluoro-11b,17-dihydroxypregna-1,4-diene-3,20-dione 341-41-3 (CAS 341-41-3)
- 2-Bromo-6-methoxyimidazo[1,2-a]pyridine (CAS 1042141-33-2)
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- (4S)-2,5,5-Trimethylthiazolidine-4-carboxylic acid (CAS 212755-85-6)
- N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine (CAS 199522-66-2)
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