1-(4-chloro-3-nitrophenyl)-4-(trifluoromethyl)[1,2,4]triazolo[4,3-a]quinoxaline CAS 343372-41-8
| CAS No. | 343372-41-8 |
| Molecular Formula | C16H7ClF3N5O2 |
| Molecular Weight | 393.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1-(4-chloro-3-nitrophenyl)-4-(trifluoromethyl)[1,2,4]triazolo[4,3-a]quinoxaline (CAS 343372-41-8), molecular formula C16H7ClF3N5O2 and molecular weight 393.71 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(4-chloro-3-nitrophenyl)-4-(trifluoromethyl)[1,2,4]triazolo[4,3-a]quinoxaline (C16H7ClF3N5O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H7ClF3N5O2 |
| Molecular Weight | 393.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related chloro Standards
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Recommended Standards
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- Brometazepam (CAS 84031-17-4)
- 4-(2H-1,3-Benzodioxol-5-yl)-1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-1,2,3-triazole-5-carbonitrile (CAS 1024414-94-5)
- (+/-)2'-Epi-orobanchol (CAS 220468-64-4)
- 6-(3-Isopropoxyphenoxy)pyridin-3-ylamine (CAS 1311137-94-6)
- N-(3-(6-(Methylsulfonyl)pyridazin-3-yl)phenyl)pentanamide (CAS 946327-49-7)
- Tert-butyl 2-(6-(2,5-dimethyl-1H-pyrrol-1-yl)pyridin-3-yl)piperidine-1-carboxylate (CAS 1352522-76-9)
- tert-Butyl 4-(2-(6-phenylpyridin-3-yl)ethyl)piperazine-1-carboxylate (CAS 2602340-81-6)
- 2-Bromo-1-(5-chloro-3-methylbenzo[b]thiophen-2-yl)ethan-1-one (CAS 175203-97-1)
- (Z)-1-[(4-Cyano-5-methyl-1,2-thiazol-3-yl)sulfonyl]-N-(4-methoxyphenyl)methanecarbohydrazonoyl cyanide (CAS 337928-23-1)
- 8-Boc-2-Fluoro-8-aza-bicyclo[3.2.1]octan-3-ol (CAS 1404196-40-2)
- 2-Bromotoluene-d7 (CAS 1185306-95-9)
- Biotinyl-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802086-28-7)
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