4-Methoxy-N-methyl-N-[3-(trifluoromethyl)-2-quinoxalinyl]benzenecarbohydrazide CAS 343372-48-5
| CAS No. | 343372-48-5 |
| Molecular Formula | C18H15F3N4O2 |
| Molecular Weight | 376.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Methoxy-N-methyl-N-[3-(trifluoromethyl)-2-quinoxalinyl]benzenecarbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Methoxy-N-methyl-N-[3-(trifluoromethyl)-2-quinoxalinyl]benzenecarbohydrazide (CAS 343372-48-5) is a high-purity analytical reference standard with the molecular formula C18H15F3N4O2 and a molecular weight of 376.33 g/mol.
Based on its molecular formula C18H15F3N4O2, 4-Methoxy-N-methyl-N-[3-(trifluoromethyl)-2-quinoxalinyl]benzenecarbohydrazide contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 376.33 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H15F3N4O2 |
| Molecular Weight | 376.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
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