N'-Methyl-N'-[3-(trifluoromethyl)quinoxalin-2-yl]furan-2-carbohydrazide CAS 343372-51-0
| CAS No. | 343372-51-0 |
| Molecular Formula | C15H11F3N4O2 |
| Molecular Weight | 336.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
N'-Methyl-N'-[3-(trifluoromethyl)quinoxalin-2-yl]furan-2-carbohydrazide (CAS 343372-51-0), molecular formula C15H11F3N4O2 and molecular weight 336.27 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C15H11F3N4O2, N'-Methyl-N'-[3-(trifluoromethyl)quinoxalin-2-yl]furan-2-carbohydrazide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 336.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H11F3N4O2 |
| Molecular Weight | 336.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Recommended Standards
- Methyl 5-cyano-2-methyl-6-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylate (CAS 303146-36-3)
- Methyl 2-phenethyl-6-(phosphonooxy)benzoate (CAS 1171921-37-1)
- 7-Amino-2-methyl-3-(3-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 863305-82-2)
- 6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-Dione (CAS 118876-58-7)
- (R)-3-((tert-butoxycarbonyl)amino)-2-(2-hydroxybenzyl)propanoic acid (CAS 1260589-03-4)
- 3-(Difluoromethyl)-2-methylbenzoic acid (CAS 848444-82-6)
- Pangamic Acid - API Standards (CAS 20858-86-0)
- Selinexor Impurity 9 (CAS 1421923-96-7)
- 5-(Aminomethyl)-4-benzyl-1,2,4-triazole-3-thiol, N-BOC protected (CAS 306935-43-3)
- O-(furan-2-ylmethyl)hydroxylamine (CAS 39854-56-3)
- 4-Cyclopropyl-6-methoxy-2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 2821754-18-9)
- 2,6,6-Trimethyl-1-cyclohexene-1-acetic acid (CAS 472-68-4)
- 2,4-Dichloro-3-fluorobenzylamine (CAS 1806354-09-5)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
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