4,8-Dimethyl-1-[(3-methylphenyl)methyl]-1,2-dihydroquinolin-2-one CAS 343374-03-8

Purity 97%+In StockPharmaceutical Standards
CAS No.343374-03-8
Molecular FormulaC19H19NO
Molecular Weight277.36 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4,8-Dimethyl-1-[(3-methylphenyl)methyl]-1,2-dihydroquinolin-2-one CAS 343374-03-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,8-Dimethyl-1-[(3-methylphenyl)methyl]-1,2-dihydroquinolin-2-one.

4,8-Dimethyl-1-[(3-methylphenyl)methyl]-1,2-dihydroquinolin-2-one (CAS 343374-03-8), molecular formula C19H19NO and molecular weight 277.36 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 4,8-Dimethyl-1-[(3-methylphenyl)methyl]-1,2-dihydroquinolin-2-one (C19H19NO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 277.36 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC19H19NO
Molecular Weight277.36 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms1

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