4-[(4-Bromophenyl)sulfanyl]-2-{[(4-methylphenyl)methyl]sulfanyl}-5,6,7,8-tetrahydroquinazoline CAS 343374-08-3
| CAS No. | 343374-08-3 |
| Molecular Formula | C22H21BrN2S2 |
| Molecular Weight | 457.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-[(4-Bromophenyl)sulfanyl]-2-{[(4-methylphenyl)methyl]sulfanyl}-5,6,7,8-tetrahydroquinazoline (C22H21BrN2S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
4-[(4-Bromophenyl)sulfanyl]-2-{[(4-methylphenyl)methyl]sulfanyl}-5,6,7,8-tetrahydroquinazoline (CAS 343374-08-3), molecular formula C22H21BrN2S2 and molecular weight 457.45 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-[(4-Bromophenyl)sulfanyl]-2-{[(4-methylphenyl)methyl]sulfanyl}-5,6,7,8-tetrahydroquinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H21BrN2S2 |
| Molecular Weight | 457.45 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Bromophenyl Standards
- 2-(4-(1-((4-Bromophenyl)sulfonyl)-1H-pyrazol-3-yl)phenoxy)pyrimidine (CAS 321998-87-2)
- N-(4-bromophenyl)-3-((2,4-dichlorobenzyl)oxy)thiophene-2-carboxamide (CAS 339098-05-4)
- N-(4-bromophenyl)-3-((2,6-dichlorobenzyl)oxy)thiophene-2-carboxamide (CAS 344270-40-2)
- 1-(2-Bromophenyl)-4-((4-bromophenyl)sulfonyl)-5-methyl-1H-1,2,3-triazole (CAS 1097884-99-5)
- 3-(4-(4-Bromophenyl)-5-((2-chlorobenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 678181-51-6)
- 3-(4-(4-Bromophenyl)-5-((3-chlorobenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 678190-60-8)
- 3-{[(4-bromophenyl)sulfanyl]methyl}-2-(4-chlorobenzoyl)-1-benzofuran (CAS 338424-00-3)
- 4-(4-(4-Bromophenyl)-5-((2-chlorobenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 477329-78-5)
Recommended Standards
- Folitixorin (~80%) (Mixture of Diastereomers) (CAS 3432-99-3)
- 8-Aminopyrene-1,3,6-trisulfonic acid (CAS 51987-58-7)
- Vericiguat Impurity 95 (CAS CATO-C4X-289695)
- N1-[(Diphenylphosphoryl)(thien-2-yl)methyl]-3-(trifluoromethyl)aniline (CAS 260437-23-8)
- (3,4-Dimethoxyphenyl)(4-fluorophenyl)methanol (CAS 844856-32-2)
- 1-(5-Bromo-2-hydroxyphenyl)-2-chloroethan-1-one (CAS 100959-21-5)
- (2-{[(furan-2-ylmethyl)(methyl)amino]methyl}phenyl)methanamine (CAS 1155480-87-7)
- (2,3,5-Trifluorophenyl)methanol (CAS 67640-33-9)
- 2-(1-Iodoethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 97571-06-7)
- 4-(1,3-Dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzoic acid (CAS 354158-53-5)
- 2-Phenyl-1,3,5-triazine (CAS 1722-18-5)
- Glicaramide (CAS 36980-34-4)
- 1-(P-tolyl)cyclohexan-1-amine (CAS 17797-15-8)
- Semaglutide impurity 236 (CAS CATO-C4X-2226236)
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