N-[(2E)-2-(4-Chlorophenyl)-2-(methoxyimino)ethyl]-4-fluorobenzamide CAS 343374-25-4

Purity 97%+In StockPharmaceutical Standards
CAS No.343374-25-4
Molecular FormulaC16H14ClFN2O2
Molecular Weight320.75 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-[(2E)-2-(4-Chlorophenyl)-2-(methoxyimino)ethyl]-4-fluorobenzamide CAS 343374-25-4 chemical structure

Description

The occurrence of N-[(2E)-2-(4-Chlorophenyl)-2-(methoxyimino)ethyl]-4-fluorobenzamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

N-[(2E)-2-(4-Chlorophenyl)-2-(methoxyimino)ethyl]-4-fluorobenzamide (CAS 343374-25-4), molecular formula C16H14ClFN2O2 and molecular weight 320.75 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C16H14ClFN2O2, N-[(2E)-2-(4-Chlorophenyl)-2-(methoxyimino)ethyl]-4-fluorobenzamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 320.75 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H14ClFN2O2
Molecular Weight320.75 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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