(5-(2-Chlorophenyl)isoxazol-3-yl)methanol CAS 343374-44-7
| CAS No. | 343374-44-7 |
| Molecular Formula | C10H8ClNO2 |
| Molecular Weight | 209.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (5-(2-Chlorophenyl)isoxazol-3-yl)methanol is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (5-(2-Chlorophenyl)isoxazol-3-yl)methanol (CAS 343374-44-7), a certified reference material (molecular formula C10H8ClNO2, MW 209.63 g/mol) for analytical method development and quality control.
The molecular framework of (5-(2-Chlorophenyl)isoxazol-3-yl)methanol (C10H8ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (5-(2-Chlorophenyl)isoxazol-3-yl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO2 |
| Molecular Weight | 209.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- (3-(3-Chlorophenyl)isoxazol-5-yl)methanol (CAS 101862-42-4)
- (5-(3-Chlorophenyl)oxazol-4-yl)methanol (CAS 1020252-88-3)
- 3-(3-Chlorophenyl)-2-cyanopropionic Acid (CAS 1082249-01-1)
- (2-(4-Chlorophenyl)oxazol-5-yl)methanol (CAS 109544-13-0)
- [5-(4-chlorophenyl)-1,3-oxazol-2-yl]methanol (CAS 109544-14-1)
- 1-(2-Chlorophenyl)-3-methyl-1H-1,2,4-triazol-5(4H)-one (CAS 109913-40-8)
- [1-(2-chlorophenyl)-1h-1,2,3-triazol-4-yl]methanol (CAS 1126635-72-0)
- 1-(4-Chlorophenyl)pyrrolidine-2,4-dione (CAS 114473-83-5)
Recommended Standards
- (3-(4-Chlorophenyl)isoxazol-5-yl)methanol (CAS 206055-90-5)
- (5-(3-Chlorophenyl)-1,2,4-oxadiazol-3-yl)methanamine (CAS 954229-47-1)
- (2-(3-Chlorophenyl)oxazol-4-yl)methanol (CAS 885272-83-3)
- (5-(3-Chlorophenyl)isoxazol-4-yl)methanol (CAS 430534-65-9)
- 1-methylpiperidine-3-carboxylic acid (CAS 5657-70-5)
- Resveratrol-(4-Hydroxyphenyl-<SUP>13</SUP>C<SUB>6</SUB>) (CAS 1185247-70-4)
- 2-(Aminomethyl)-4-cyano-6-(difluoromethyl)pyridine-3-methanol (CAS 1805569-32-7)
- 1-Cyanato-4-nitrobenzene (CAS 1129-38-0)
- 2-(((4-Methoxyphenyl)amino)methylene)cyclohexane-1,3-dione (CAS 62370-45-0)
- 3',4'-Dichloro-[1,1'-biphenyl]-2-carbaldehyde (CAS 924868-83-7)
- Cefozopran Dihydrochloride (CAS 1262200-57-6)
- 1,3-Bis(5-bromo-3-methylpyridin-2-yl)urea (CAS 1263208-76-9)
- 5-Bromo-2-(5-chloro-1H-indol-2-yl)-3-fluorophenol (CAS 1370468-13-5)
- 81988-89-8 UH11FDQ454 Ramoplanin A(sub 3) Ramoplanin A3 (S)-2-(3-Chloro-4-hydroxyphenyl)-N-(N(sup 2)-((2Z,4Z)-8-methyl-2,4-nonadienoyl)-(S)-asparaginyl-(2S,3S)-3-hydroxyasparaginyl-(R)-2-(p-hydroxyphenyl)glycyl-(R)-ornithyl-(2R,3R)-allothreonyl-2-(p-hydroxyphenyl)glycyl-2-(p-hydroxyphenyl)glycyl-(2S,3S)-allothreonyl-(S)-phenylalanyl-(R)-ornithyl-(S)-2-(p-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycyl-(2R,3R)-allothreonyl-(S)-2-(p-hydroxyphenyl)glycylglycyl-(S)-leucyl-(R)-alanyl)glycine psi1-lactone Ramoplanin A 1 (peptide moiety), 1-(N(sup 2)-methyl-1-oxo-2,4-nonadienyl)-L-asparagine)-11-(L-2-(4-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycine)-, (Z,Z)- UNII-UH11FDQ454 (CAS 81988-89-8)
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