3-(2-Chlorobenzoyl)-4-(4-chlorophenyl)-1-methylpyrrolidine CAS 343374-80-1
| CAS No. | 343374-80-1 |
| Molecular Formula | C18H17Cl2NO |
| Molecular Weight | 334.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(2-Chlorobenzoyl)-4-(4-chlorophenyl)-1-methylpyrrolidine (C18H17Cl2NO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 3-(2-Chlorobenzoyl)-4-(4-chlorophenyl)-1-methylpyrrolidine (CAS 343374-80-1), a certified reference material (molecular formula C18H17Cl2NO, MW 334.24 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2-Chlorobenzoyl)-4-(4-chlorophenyl)-1-methylpyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H17Cl2NO |
| Molecular Weight | 334.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorobenzoyl Standards
- 5-(4-Chlorobenzoyl)-2-(4-chlorophenyl)-1,3-thiazole (CAS 338779-61-6)
- Ethyl 2-(5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl)propanoate (CAS 33369-43-6)
- N-(2-(4-Chlorobenzoyl)-4,5-dimethoxyphenyl)acetamide (CAS 886493-95-4)
- 1-{[(4-chlorobenzoyl)oxy]imino}cyclododecane (CAS 252730-97-5)
- 1-(4-Chlorobenzoyl)-4-(6-chloropyridin-2-yl)piperazine (CAS 339107-34-5)
- 4-(2-Chlorobenzoyl)-N,N-dimethylpiperazine-1-sulfonamide (CAS 712345-55-6)
- 2-(4-(2-Chlorobenzoyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-3-yl)acetic acid (CAS 439096-40-9)
- N-(7-(4-chlorobenzoyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (CAS 886493-78-3)
Recommended Standards
- 2,5-Dichloro-4-pyrrolidinomethyl benzophenone (CAS 898776-83-5)
- 3,4-Dichloro-4-pyrrolidinomethyl benzophenone (CAS 898776-85-7)
- 2,5-Dichloro-2-pyrrolidinomethyl benzophenone (CAS 898774-97-5)
- 3,5-Dichloro-4-pyrrolidinomethyl benzophenone (CAS 898776-87-9)
- 2,2-Difluoro-N-(1-(1-methyl-1h-pyrazol-3-yl)ethyl)ethan-1-amine (CAS 1245807-11-7)
- Methyl 6-(2,4-difluorophenyl)pyridine-3-carboxylate (CAS 938433-58-0)
- 2-[(2,3-Dihydro-1,4-benzodioxin-6-yl)sulfonyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid (CAS 1008266-08-7)
- 3-Benzyl-3-azabicyclo[4.1.0]heptan-6-amine (CAS 1000934-01-9)
- 4-[(4-Methylphenyl)methyl]-3-{1-[4-(trifluoromethyl)benzoyl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775549-33-1)
- 4-Bromo-5,6,7,8-tetrahydro-[1,5]naphthyridine-2-carbonitrile (CAS 1263211-32-0)
- 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-butanoic acid (CAS 35340-62-6)
- Desloratadine Impurity 60 (CAS CATO-C4X-143060)
- 4-(2-Fluoroethoxy)-2-methylaniline (CAS 1365942-21-7)
- Tau Peptide (401-411)-Lys-Lys trifluoroacetate salt (CAS 2022956-59-6)
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