| CAS No. | 343374-89-0 |
| Molecular Formula | C11H11F3O2S |
| Molecular Weight | 264.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
1-Methyl-4-(3,4,4-trifluorobut-3-ene-1-sulfonyl)benzene (CAS 343374-89-0), molecular formula C11H11F3O2S and molecular weight 264.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Methyl-4-(3,4,4-trifluorobut-3-ene-1-sulfonyl)benzene (C11H11F3O2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Methyl-4-(3,4,4-trifluorobut-3-ene-1-sulfonyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C11H11F3O2S |
| Molecular Weight | 264.26 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |