3-[(2,4-Dichlorophenyl)methanesulfonyl]-5-methyl-1,2-thiazole-4-carbonitrile CAS 343375-35-9
| CAS No. | 343375-35-9 |
| Molecular Formula | C12H8Cl2N2O2S2 |
| Molecular Weight | 347.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 347.24 g/mol gives 3-[(2,4-Dichlorophenyl)methanesulfonyl]-5-methyl-1,2-thiazole-4-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-[(2,4-Dichlorophenyl)methanesulfonyl]-5-methyl-1,2-thiazole-4-carbonitrile (CAS 343375-35-9), molecular formula C12H8Cl2N2O2S2 and molecular weight 347.24 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C12H8Cl2N2O2S2, 3-[(2,4-Dichlorophenyl)methanesulfonyl]-5-methyl-1,2-thiazole-4-carbonitrile contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 347.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-[(2,4-Dichlorophenyl)methanesulfonyl]-5-methyl-1,2-thiazole-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8Cl2N2O2S2 |
| Molecular Weight | 347.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Dichlorophenyl Standards
- 3-[(2,6-Dichlorophenyl)methanesulfonyl]-5-methyl-1,2-thiazole-4-carbonitrile (CAS 339021-09-9)
- 6-(3,4-Dichlorophenyl)-4-(4-ethylphenyl)-4,5-dihydropyridazin-3(2H)-one (CAS 73685-02-6)
- 2-{[(3,4-dichlorophenyl)methyl]sulfanyl}-5-phenylpyrimidine (CAS 344282-11-7)
- 3-[(2,4-Dichlorophenyl)methyl]-6-(phenylsulfanyl)pyridazine (CAS 241488-45-9)
- N-(3,4-Dichlorophenyl)-2-(2-methyl-3,5-dioxothiomorpholino)acetamide (CAS 868215-99-0)
- 5-({[(2,4-dichlorophenyl)methyl]sulfanyl}methylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 477866-44-7)
- 2-{[(3,4-dichlorophenyl)methyl]sulfanyl}-5-methoxy-4-(methylsulfanyl)pyrimidine (CAS 339276-06-1)
- 2-(2,6-Dichlorophenyl)-N-cyclopropyl-3H-imidazo[4,5-c]pyridine-4-carboxamide (CAS 1337880-69-9)
Recommended Standards
- 2,2-Difluoro-2-phenoxy-N-[4-(trifluoromethoxy)phenyl]acetamide (CAS 338791-88-1)
- (S)-3,5-Dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide (CAS 84225-95-6)
- 5-Chloro-4-{[(4-chlorophenyl)methoxy]methyl}-1-methyl-3-phenyl-1H-pyrazole (CAS 318248-49-6)
- Tert-butyl (R)-4-(2,4-dichloropyrimidin-5-yl)-2-methylpiperazine-1-carboxylate (CAS 1821293-56-4)
- Ethyl 7-ethoxybenzo[d]imidazo[2,1-b]thiazole-2-carboxylate (CAS 81022-06-2)
- (R)-2-fluoro-6-(pyrrolidin-2-yl)benzonitrile (CAS 1213012-59-9)
- 6-Fluoro-2-(2-fluorophenyl)quinolin-4-amine (CAS 189877-87-0)
- 2-Hydroxy-4-oxo-4-phenylbut-2-enoic acid (CAS 113416-61-8)
- [2-(piperidine-1-sulfonyl)phenyl]methanamine hydrochloride (CAS 918812-19-8)
- 2',3',4',5',6'-Pentafluoro[1,1'-biphenyl]-3-carboxylic acid (CAS 29779-00-8)
- 3-Bromo-4-(tert-butoxy)aniline (CAS 1250972-10-1)
- 2-[4-Chloro-3-(trifluoromethyl)benzenesulfonamido]-3-phenylpropanoic acid (CAS 1008052-19-4)
- 2-{4-[(dimethylamino)methyl]piperidin-1-yl}pyrimidin-4-amine (CAS 1712870-30-8)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
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