(E)-3-(3-(dimethylamino)acryloyl)-5-hydroxy-5-methyl-4-phenyl-1,5-dihydro-2H-pyrrol-2-one CAS 343375-37-1
| CAS No. | 343375-37-1 |
| Molecular Formula | C16H18N2O3 |
| Molecular Weight | 286.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-3-(3-(dimethylamino)acryloyl)-5-hydroxy-5-methyl-4-phenyl-1,5-dihydro-2H-pyrrol-2-one (C16H18N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
(E)-3-(3-(dimethylamino)acryloyl)-5-hydroxy-5-methyl-4-phenyl-1,5-dihydro-2H-pyrrol-2-one (CAS 343375-37-1), molecular formula C16H18N2O3 and molecular weight 286.33 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (E)-3-(3-(dimethylamino)acryloyl)-5-hydroxy-5-methyl-4-phenyl-1,5-dihydro-2H-pyrrol-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H18N2O3 |
| Molecular Weight | 286.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
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Recommended Standards
- (E)-2-(2-((2-(2-fluorophenyl)hydrazono)methyl)-1H-pyrrol-1-yl)thiazole (CAS 692287-96-0)
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- (E)-2-((3-methylbenzylidene)amino)-5-phenylfuran-3-carbonitrile (CAS 478033-29-3)
- (R,S)-In-Quinox (CAS 2095128-11-1)
- (2S,4S)-1-(tert-Butoxycarbonyl)-4-(2-chloro-5-fluorophenoxy)-2-pyrrolidinecarboxylic acid (CAS 1217642-26-6)
- 4-[1-(propan-2-yl)-1H-1,2,3-triazol-4-yl]-2,3,6,7-tetrahydro-1H-azepine dihydrochloride (CAS 1864052-66-3)
- 2-Bromo-4-(((tert-butyldimethylsilyl)oxy)methyl)-5-methylthiazole (CAS 1477479-26-7)
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- Olopatadine Impurity 70 (CAS CATO-C4X-171870)
- 2-(1-Methyl-1H-imidazol-2-yl)piperidine (CAS 933713-92-9)
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