5-Chloro-4-((2-chlorobenzyl)thio)-6-methylpyrimidin-2-amine CAS 343375-76-8
| CAS No. | 343375-76-8 |
| Molecular Formula | C12H11Cl2N3S |
| Molecular Weight | 300.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 5-Chloro-4-((2-chlorobenzyl)thio)-6-methylpyrimidin-2-amine (CAS 343375-76-8), a certified reference material (molecular formula C12H11Cl2N3S, MW 300.21 g/mol) for analytical method development and quality control.
5-Chloro-4-((2-chlorobenzyl)thio)-6-methylpyrimidin-2-amine (C12H11Cl2N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11Cl2N3S |
| Molecular Weight | 300.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 4-Fluorophenyl 5-(trifluoromethyl)-pyridin-2-ylcarbamate (CAS 1993323-73-1)
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- 4-[(2,3,5,6-tetrafluorophenoxy)methyl]benzoic acid (CAS 374922-67-5)
- Tetrahydro-4H-thiopyran-4-one O-(3-bromobenzyl) oxime (CAS 866155-14-8)
- Isobutyryl Bromide (CAS 2736-37-0)
- 1-(2-Bromophenyl)cyclopropanecarbonitrile (CAS 124276-75-1)
- 1-(3-Methylbenzoyl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine (CAS 941189-17-9)
- Buta-2,3-dienoic acid (CAS 5732-10-5)
- 6-Phenyl-[2,2'-bipyridine]-4-carboxylic acid (CAS 282550-57-6)
- 1-(2-Fluoroethyl)piperidine (CAS 45705-52-0)
- {3-[bis(3-aminopropyl)amino]propyl}dimethylamine (CAS 71326-30-2)
- 1-(3-Bromo-2,4,6-trifluoro-phenyl)-2,2,2-trifluoro-ethanone (CAS 1208076-09-8)
- 4-cyclopropyl-12-methyl-3,5,6,8-tetraazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2,4,10,12-pentaen-7-one (CAS 1181458-12-7)
- Crustacean Cardioactive Peptide (CCAP) (CAS 309247-84-5)
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