Methyl 3-((2,4-dichlorobenzyl)oxy)thiophene-2-carboxylate CAS 343375-78-0
| CAS No. | 343375-78-0 |
| Molecular Formula | C13H10Cl2O3S |
| Molecular Weight | 317.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 3-((2,4-dichlorobenzyl)oxy)thiophene-2-carboxylate (CAS 343375-78-0) is a high-purity analytical reference standard with the molecular formula C13H10Cl2O3S and a molecular weight of 317.19 g/mol.
Methyl 3-((2,4-dichlorobenzyl)oxy)thiophene-2-carboxylate (C13H10Cl2O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 3-((2,4-dichlorobenzyl)oxy)thiophene-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10Cl2O3S |
| Molecular Weight | 317.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
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Recommended Standards
- Azetidin-1-yl(3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone (CAS 2434717-24-3)
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- Pcb No. 23 (CAS 55720-44-0)
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- 4-Hydroxy-3-oxobutanoic acid (CAS 162369-88-2)
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