6-((2-Chlorobenzyl)thio)-5-nitroimidazo[2,1-b]thiazole CAS 343376-27-2
| CAS No. | 343376-27-2 |
| Molecular Formula | C12H8ClN3O2S2 |
| Molecular Weight | 325.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 6-((2-Chlorobenzyl)thio)-5-nitroimidazo[2,1-b]thiazole (C12H8ClN3O2S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 325.79 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 6-((2-Chlorobenzyl)thio)-5-nitroimidazo[2,1-b]thiazole (CAS 343376-27-2), a certified reference material (molecular formula C12H8ClN3O2S2, MW 325.79 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-((2-Chlorobenzyl)thio)-5-nitroimidazo[2,1-b]thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8ClN3O2S2 |
| Molecular Weight | 325.79 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Chlorobenzyl Standards
- (4-(5-((3-Chlorobenzyl)amino)pyrazin-2-yl)phenyl)methanol (CAS 920527-78-2)
- 2-(2-((3-Chlorobenzyl)thio)-5-(hydroxymethyl)-1H-imidazol-1-yl)-N-methylacetamide (CAS 923138-76-5)
- 2-(2-Chlorobenzyl)-4,4-dimethyl-5-(pentyloxy)isoxazolidin-3-one (CAS 81778-78-1)
- 1-(4-Chlorobenzyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2-amine (CAS 150493-34-8)
- 4-[(4-Chlorobenzyl)oxy]-3-ethoxybenzoyl chloride (CAS 1160251-15-9)
- 4-[(3-Chlorobenzyl)oxy]-3-ethoxybenzoyl chloride (CAS 1160251-21-7)
- 4-[(2-Chlorobenzyl)oxy]-3-ethoxybenzoyl chloride (CAS 1160260-38-7)
- 2-(3-(2-Chlorobenzyl)-2,4-dioxo-3,4-dihydropyrido[2,3-d]pyrimidin-1(2H)-yl)acetonitrile (CAS 902964-20-9)
Recommended Standards
- 5-Chloro-N-[(1E)-(dimethylamino)methylidene]-3-phenyl-1H-indole-2-carboxamide (CAS 338401-01-7)
- 6-{[(4-chlorophenyl)methyl]sulfanyl}-5-nitroimidazo[2,1-b][1,3]thiazole (CAS 343376-23-8)
- 5-(2-Chlorophenyl)-N-(2-ethylphenyl)furan-2-carboxamide (CAS 618401-47-1)
- 6-Chloro-2-(4-isopropylphenyl)quinoline-4-carboxylic acid (CAS 897560-12-2)
- 5-Iodopyrazolo[1,5-a]pyridine-3-carboxylic acid (CAS 1352397-99-9)
- (1R)-1-(5-methyl-1,3,4-oxadiazol-2-yl)ethanamine (CAS 1799497-98-5)
- (S)-2-amino-N,3-dimethyl-N-(1-methylpiperidin-4-yl)butanamide (CAS 1308560-22-6)
- 6-(1H-pyrrol-1-yl)benzo[d][1,3]dioxol-5-amine (CAS 1242268-16-1)
- Ethyl 2-(thiophen-2-yl)pyrimidine-5-carboxylate (CAS 954227-49-7)
- 4-Methoxy-N-(2-(2-(4-methoxyphenyl)thiazol-4-yl)ethyl)benzamide (CAS 863556-07-4)
- Methyl 3-Bromo-2-fluorobenzoate (CAS 206551-41-9)
- 2,2'-(Buta-1,3-diyne-1,4-diyl)dianiline (CAS 31661-58-2)
- Posaconazole Impurity 2 (CAS 2243786-00-5)
- D-Ser12-Semaglutide (CAS CATO-C4X-2226240)
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