4,4'-Oxybis[3-(trifluoromethyl)aniline] CAS 344-48-9
| CAS No. | 344-48-9 |
| Molecular Formula | C14H10F6N2O |
| Molecular Weight | 336.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,4'-Oxybis[3-(trifluoromethyl)aniline] is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4,4'-Oxybis[3-(trifluoromethyl)aniline] (CAS 344-48-9), a certified reference material (molecular formula C14H10F6N2O, MW 336.23 g/mol) for analytical method development and quality control.
The molecular framework of 4,4'-Oxybis[3-(trifluoromethyl)aniline] (C14H10F6N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4,4'-Oxybis[3-(trifluoromethyl)aniline] under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H10F6N2O |
| Molecular Weight | 336.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Oxybis Standards
- 4,4'-(Oxybis(methylene))bis((trifluoromethyl)benzene) (CAS 162404-64-0)
- 2,2'-(Oxybis(methylene))bis(4-(trifluoromethyl)pyrimidine) (CAS 1346808-72-7)
- 2,2'-(Oxybis(methylene))bis(4-methylquinazoline) (CAS 2387695-89-6)
- 1,1'-(((Oxybis(ethane-2,1-diyl))bis(oxy))bis(2,1-phenylene))bis(ethan-1-one) (CAS 89579-20-4)
- 1,1’-[Oxybis(4,1-phenylene)]bis(2-hydroxy-2-methyl-1-propanone) (CAS 71868-15-0)
- Oxybis(propane-1,2-diyl) dibenzoate (CAS 94-03-1)
- Oxybis(propane-3,1-diyl) dibenzoate (CAS 94-51-9)
- 4,4'-(Oxybis(4,1-phenylene))dipyridine (CAS 133416-11-2)
Recommended Standards
- 3-Bromo-N-(2-(3,5-dimethyl-1H-pyrazol-1-yl)propyl)benzamide (CAS 890604-34-9)
- 4-Bromo-N-(diphenylmethylene)benzenamine (CAS 53847-33-9)
- 3-Bromo-9-p-tolyl-9H-carbazole (CAS 731016-44-7)
- 9-Benzyl-3-bromo-9H-carbazole (CAS 339576-55-5)
- 1-(2-Chloropropyl)piperidine hydrochloride (CAS 41821-48-1)
- 1-(4-Chlorophenyl)-3-(3-nitrophenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-98-9)
- 9-Methylanthracene-d12 (CAS 6406-97-9)
- Cefazolin Impurity 83 (CAS CATO-C4X-157783)
- 3-[1-butyl-5-(diethylsulfamoyl)-1h-1,3-benzodiazol-2-yl]propanoic acid (CAS 729582-35-8)
- 3,3,4,5,5,5-Hexafluoro-2-pentanone (CAS 60249-67-4)
- 4-Cyclobutoxy-6-methoxypyrimidin-2-amine (CAS 552880-94-1)
- Fondaparinux Sodium Impurity 11 (CAS CATO-C4X-205211)
- methyl 3-[(4-methylphenyl)amino]propanoate (CAS 21911-85-3)
- [3-31]-Semaglutide D (Sodium salt) (CAS CATO-C4X-2226119)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com