2'-(Trifluoromethyl)acetanilide CAS 344-62-7
| CAS No. | 344-62-7 |
| Molecular Formula | C9H8F3NO |
| Molecular Weight | 203.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2'-(Trifluoromethyl)acetanilide (C9H8F3NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2'-(Trifluoromethyl)acetanilide (CAS 344-62-7) is a high-purity analytical reference standard with the molecular formula C9H8F3NO and a molecular weight of 203.16 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2'-(Trifluoromethyl)acetanilide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8F3NO |
| Molecular Weight | 203.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 3-(3-(Trifluoromethyl)-1h-pyrazol-1-yl)butanenitrile (CAS 1006319-93-2)
- 3-(5-Methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)propanenitrile (CAS 1006343-68-5)
- 3-[3-methyl-5-(trifluoromethyl)-1h-pyrazol-1-yl]propanenitrile (CAS 1006461-11-5)
- 3-(Trifluoromethyl)-7,8-dihydro-5H-pyrano[4,3-b]pyridine (CAS 1196151-73-1)
- 1-(5-(Trifluoromethyl)pyridin-2-yl)propan-1-one (CAS 120427-48-7)
- 5-(Trifluoromethyl)-2,3-dihydro-1-benzofuran-3-amine (CAS 1243205-10-8)
- 6-(Trifluoromethyl)-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine (CAS 1260657-41-7)
- 2-(1-Ethyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)acetonitrile (CAS 1260659-32-2)
Recommended Standards
- 2-(Trifluoromethyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS 741737-16-6)
- 2,2,2-Trifluoro-1-(2-(methylamino)phenyl)ethanone (CAS 202270-41-5)
- 2-(Trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine (CAS 737754-25-5)
- 2,2,2-Trifluoro-1-(4-(methylamino)phenyl)ethanone (CAS 75822-12-7)
- 5-(2-Chlorophenyl)nicotinonitrile (CAS 1267467-92-4)
- [1-((S)-2-Amino-3-methyl-butyryl)-piperidin-4-yl]-isopropyl-carbamic acid benzyl ester (CAS 1354000-72-8)
- Methyl (2E,4E)-5-phenylpenta-2,4-dienoate (CAS 1516-24-1)
- Methyl (2R)-2-amino-5-(carbamoylamino)pentanoate (CAS 1820583-50-3)
- (S)-1-(2-Aminoethyl)-N-benzyl-N-methylpyrrolidin-3-amine (CAS 1353994-12-3)
- Relugolix Impurity 81 (CAS CATO-C4X-242981)
- 2-Fluoro-6-formylbenzonitrile (CAS 1261823-28-2)
- 2-(Benzo[d][1,3]dioxol-5-yl)-8-methylquinoline-4-carboxylic acid (CAS 932796-11-7)
- 5-ethynyl-1H-pyrazolo[4,3-b]pyridine (CAS 1374652-56-8)
- Semaglutide impurity 96 (CAS CATO-C4X-222696)
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