3-[(4-tert-Butylphenyl)methoxy]-N-(2-chlorophenyl)thiophene-2-carboxamide CAS 344270-72-0
| CAS No. | 344270-72-0 |
| Molecular Formula | C22H22ClNO2S |
| Molecular Weight | 399.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-[(4-tert-Butylphenyl)methoxy]-N-(2-chlorophenyl)thiophene-2-carboxamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-[(4-tert-Butylphenyl)methoxy]-N-(2-chlorophenyl)thiophene-2-carboxamide (CAS 344270-72-0), molecular formula C22H22ClNO2S and molecular weight 399.93 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-[(4-tert-Butylphenyl)methoxy]-N-(2-chlorophenyl)thiophene-2-carboxamide (C22H22ClNO2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 399.93 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H22ClNO2S |
| Molecular Weight | 399.93 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related tert Standards
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Recommended Standards
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- 1-{[2-(4-chloro-2-methylphenoxy)-1,3-thiazol-5-yl]methyl}-4-phenylpiperazine (CAS 439097-09-3)
- 2-Methyl-3-(4-methylcyclohexyl)propanoic acid (CAS 1518681-72-5)
- 3-Bromofluoranthene (CAS 13438-50-1)
- 1-(4-Bromo-2-(methoxymethyl)phenyl)-2-methylpiperidine (CAS 1141474-35-2)
- 2-Chloro-N-(2,5-dimethylphenyl)-2-phenylacetamide (CAS 726150-60-3)
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- Dexrazoxane Impurity 18 (CAS CATO-C4X-202018)
- 2-(azepan-1-yl)cyclohexan-1-one (CAS 1157735-52-8)
- 2-Chloro-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid (CAS 1367932-33-9)
- 1-[(2-Fluorophenyl)methyl]-1H-pyrazol-4-amine (CAS 925634-52-2)
- Autocamtide-2-Related Inhibitory Peptide TFA (CAS 167114-91-2（free base）)
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