5-(((2,4-Dichlorobenzyl)thio)methyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione CAS 344272-72-6
| CAS No. | 344272-72-6 |
| Molecular Formula | C16H13Cl2N3S2 |
| Molecular Weight | 382.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 382.33 g/mol gives 5-(((2,4-Dichlorobenzyl)thio)methyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(((2,4-Dichlorobenzyl)thio)methyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 344272-72-6), molecular formula C16H13Cl2N3S2 and molecular weight 382.33 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(((2,4-Dichlorobenzyl)thio)methyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (C16H13Cl2N3S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(((2,4-Dichlorobenzyl)thio)methyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13Cl2N3S2 |
| Molecular Weight | 382.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Dichlorobenzyl Standards
- 5-(((2,6-Dichlorobenzyl)thio)methyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 344269-75-6)
- 4-(1-(2,4-Dichlorobenzyl)-3,5-dimethyl-1h-pyrazol-4-yl)-5-ethyl-4h-1,2,4-triazole-3-thiol (CAS 1006358-33-3)
- 6-((2,4-Dichlorobenzyl)thio)-9-isobutyl-9H-purin-2-amine (CAS 94094-16-3)
- Methyl 4-(2,4-dichlorobenzyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxylate (CAS 338393-80-9)
- 4-((3,4-Dichlorobenzyl)thio)-N-ethyl-6-(trifluoromethyl)pyrimidin-2-amine (CAS 339011-10-8)
- 2-(4-(3-(2,6-Dichlorobenzyl)-2-methyl-4-oxopyridin-1(4H)-yl)phenyl)acetonitrile (CAS 478246-06-9)
- 2-((2,6-Dichlorobenzyl)thio)-1-(prop-2-yn-1-yl)-4,5-dipropyl-1H-imidazole (CAS 338966-13-5)
- 2-((3,4-Dichlorobenzyl)thio)-5-(2-(methylthio)phenyl)-1,3,4-oxadiazole (CAS 339015-33-7)
Recommended Standards
- 4-Allyl-3-((2,4-dichlorobenzyl)thio)-5-(thiophen-2-yl)-4H-1,2,4-triazole (CAS 577960-27-1)
- 2Z,6Z-Farnesyl diphosphate (CAS 27248-37-9)
- 5-(2,6-Difluorobenzoyl)-7-(trifluoromethyl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline (CAS 861206-91-9)
- 2,5-Bis-(4-fluorophenyl)-1,3,4-oxadiazole (CAS 324-81-2)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-bromobenzoic acid (CAS 2243505-11-3)
- 2-Amino-N-cyclopropyl-N-((1-methylpiperidin-3-yl)methyl)acetamide (CAS 1353974-93-2)
- Dl-Isoleucine (CAS 443-79-8)
- (R)-1-(3,4-Dichlorobenzyl)pyrrolidin-3-amine hydrochloride (CAS 1939213-82-7)
- Roxatidine Impurity 43 (CAS 100-83-4)
- Ganoderic acid Y (CAS 86377-52-8)
- 1-(3,4-Difluorophenyl)-5-propyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1097117-88-8)
- N-(3-(tert-Butyl)isoxazol-5-yl)-2,6-dipropoxybenzamide (CAS 82558-51-8)
- rel-(1R,2S,4R,5S)-5-Aminobicyclo[2.2.1]heptan-2-ol (CAS 178111-37-0)
- Angiotensin III Antipeptide (CAS 133605-55-7)
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