5-[(1Z)-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}methyl]-3-phenyl-2,1-benzoxazole CAS 344276-26-2
| CAS No. | 344276-26-2 |
| Molecular Formula | C20H12ClF3N4O |
| Molecular Weight | 416.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-[(1Z)-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}methyl]-3-phenyl-2,1-benzoxazole (C20H12ClF3N4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 5-[(1Z)-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}methyl]-3-phenyl-2,1-benzoxazole (CAS 344276-26-2), a certified reference material (molecular formula C20H12ClF3N4O, MW 416.78 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H12ClF3N4O |
| Molecular Weight | 416.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- N-(4-chlorophenyl)-3-phenyl-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine-1-carboxamide (CAS 251307-17-2)
- (5-(1,3-Dioxolan-2-yl)thiophen-2-yl)(cyclopentyl)methanone (CAS 898772-54-8)
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- 4-Chloro-5-methyl-1H-indole (CAS 162100-43-8)
- [(1-phenyl-1h-pyrazol-4-yl)methyl](propan-2-yl)amine (CAS 1152898-13-9)
- 6-amino-1,2,3,4-tetrahydronaphthalen-1-ol (CAS 503832-26-6)
- Ethyl 4-oxo-3-(trifluoroacetyl)cyclohexane-1-carboxylate (CAS 1394042-16-0)
- 2-Phenyloxazole-4-carbaldehyde (CAS 20771-08-8)
- 2-((4,6-Dihydroxy-1,3,5-triazin-2-yl)amino)-4H-benzo[e][1,3]thiazin-4-one (CAS 488090-15-9)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
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