2-(2-Chloropyridin-3-yl)-1-(2-fluorobenzyl)-5,6-dimethyl-1H-benzo[d]imidazole CAS 344279-73-8
| CAS No. | 344279-73-8 |
| Molecular Formula | C21H17ClFN3 |
| Molecular Weight | 365.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-(2-Chloropyridin-3-yl)-1-(2-fluorobenzyl)-5,6-dimethyl-1H-benzo[d]imidazole (C21H17ClFN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 365.83 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-(2-Chloropyridin-3-yl)-1-(2-fluorobenzyl)-5,6-dimethyl-1H-benzo[d]imidazole (CAS 344279-73-8) is a high-purity analytical reference standard with the molecular formula C21H17ClFN3 and a molecular weight of 365.83 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(2-Chloropyridin-3-yl)-1-(2-fluorobenzyl)-5,6-dimethyl-1H-benzo[d]imidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H17ClFN3 |
| Molecular Weight | 365.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloropyridin Standards
- 2-(2-Chloropyridin-3-yl)-1-(3-fluorobenzyl)-5,6-dimethyl-1H-benzo[d]imidazole (CAS 860787-69-5)
- 2-(2-Chloropyridin-3-yl)-1-(4-fluorobenzyl)-5,6-dimethyl-1H-benzo[d]imidazole (CAS 344279-40-9)
- Ethyl (2-((2-chloropyridin-3-yl)amino)-1,1,1,3,3,3-hexafluoropropan-2-yl)carbamate (CAS 340033-55-8)
- (4Z)-1-(6-Chloropyridin-2-yl)-4-({[3-(trifluoromethyl)phenyl]amino}methylidene)-4,5-dihydro-1H-pyrazol-5-one (CAS 320419-29-2)
- 2-(6-Chloropyridin-3-yl)-5-methylthiazol-4-yl 2,4-difluorobenzoate (CAS 400081-01-8)
- 5-Chloropyridin-3-yl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate (CAS 1041426-05-4)
- N-(5-chloropyridin-2-yl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide (CAS 439111-83-8)
- N-(2-Chloropyridin-3-yl)-2-{[(4-methoxyphenyl)methyl]amino}pyridine-3-carboxamide (CAS 132312-45-9)
Recommended Standards
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