2-(3-Chlorophenyl)-4-oxo-4-phenylbutanoic acid CAS 344280-12-2
| CAS No. | 344280-12-2 |
| Molecular Formula | C16H13ClO3 |
| Molecular Weight | 288.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(3-Chlorophenyl)-4-oxo-4-phenylbutanoic acid.
CATO supplies 2-(3-Chlorophenyl)-4-oxo-4-phenylbutanoic acid (CAS 344280-12-2), a certified reference material (molecular formula C16H13ClO3, MW 288.73 g/mol) for analytical method development and quality control.
The molecular framework of 2-(3-Chlorophenyl)-4-oxo-4-phenylbutanoic acid (C16H13ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13ClO3 |
| Molecular Weight | 288.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Related Chlorophenyl Standards
- 4-(4-Chlorophenyl)-4-oxo-3-phenylbutanoic acid (CAS 101272-92-8)
- 4-(4-Chlorophenyl)-4-oxo-2-phenylbutanoic acid (CAS 116776-52-4)
- (E)-1-(4-Chlorophenyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one (CAS 152809-69-3)
- 1-(3-Chlorophenyl)-3-(2-hydroxy-4-methylphenyl)propane-1,3-dione (CAS 1573547-61-1)
- (2-Chlorophenyl)(7-methoxy-1-benzofuran-2-yl)methanol (CAS 477858-47-2)
- (3-(4-Chlorophenyl)oxiran-2-yl)(4-methoxyphenyl)methanone (CAS 27547-08-6)
- 1-(4-Chlorophenyl)-3-(3-hydroxy-4-methoxyphenyl)prop-2-en-1-one (CAS 934022-20-5)
- 1-(4-Chlorophenyl)-5-cyano-N-ethyl-N-methyl-1H-pyrazole-4-carboxamide (CAS 98476-37-0)
Recommended Standards
- 2-(3-Chloro-4-methoxyphenyl)-6-methyl-2H-benzo[d][1,2,3]triazol-5-amine (CAS 356085-76-2)
- 2-(4-Aminobenzoyl)-2'-chloroacetanilide (CAS 62253-94-5)
- 2-((2-Amino-5-((4-chlorophenyl)ethynyl)pyrimidin-4-yl)amino)ethanol (CAS 393857-13-1)
- 2-(4-Chlorophenyl)-4-oxo-4-phenylbutanoic acid (CAS 39206-70-7)
- 5,11-Dimethyl-2-((1-(piperidin-4-yl)-1H-pyrazol-4-yl)amino)-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one (CAS 1628614-50-5)
- 5-methyl-3-phenylimidazolidine-2,4-dione (CAS 33558-00-8)
- 2-Amino-N-(3-methylphenyl)propanamidehydrochloride (CAS 1236261-20-3)
- 2-(2-(Azetidin-1-ylmethyl)benzoyl)benzonitrile (CAS 898754-44-4)
- Pyrido[2,3-d]pyridazin-5(6H)-one, 8-(1-methylethyl)-2-(trifluoromethyl)- (CAS 2890563-24-1)
- (S)-3-(Benzyloxy)-4-hydroxy-5-methylfuran-2(5H)-one (CAS 124400-11-9)
- 2-(Benzylthio)-N-(5-(2-(phenylthio)ethyl)-1,3,4-oxadiazol-2-yl)acetamide (CAS 923491-82-1)
- Ceftazidime Dihydrochloride (CAS 73547-70-3)
- 1-(Bicyclo[1.1.0]butan-1-yl)ethanone (CAS 24464-70-8)
- Neuropeptide FF (CAS 99566-27-5)
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