Methyl 4-(4-chlorophenyl)-2-(2,3-dichlorophenyl)-4-oxobutanoate CAS 344280-40-6
| CAS No. | 344280-40-6 |
| Molecular Formula | C17H13Cl3O3 |
| Molecular Weight | 371.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 4-(4-chlorophenyl)-2-(2,3-dichlorophenyl)-4-oxobutanoate is closely related to a steroid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Methyl 4-(4-chlorophenyl)-2-(2,3-dichlorophenyl)-4-oxobutanoate (CAS 344280-40-6), a certified reference material (molecular formula C17H13Cl3O3, MW 371.64 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 4-(4-chlorophenyl)-2-(2,3-dichlorophenyl)-4-oxobutanoate (C17H13Cl3O3) is characterized by a steroid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H13Cl3O3 |
| Molecular Weight | 371.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Related Methyl Standards
- Methyl 4-(4-chlorophenyl)-2-(2,4-dichlorophenyl)-4-oxobutanoate (CAS 344280-62-2)
- Methyl 4-(4-chlorophenyl)-2-(2,6-dichlorophenyl)-4-oxobutanoate (CAS 344280-86-0)
- (1-(2-Chlorophenyl)-3-(2,4-dichloro-5-fluorophenyl)-1H-pyrazol-4-yl)methanol (CAS 618441-95-5)
- (1-(3-Chlorophenyl)-3-(2,4-dichloro-5-fluorophenyl)-1H-pyrazol-4-yl)methanol (CAS 618441-75-1)
- 2-(2-Chlorophenyl)-5-((2,4-dichlorobenzyl)thio)-1,3,4-oxadiazole (CAS 329023-83-8)
- (4-(4-Chlorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl)-L-proline (CAS 1102852-18-5)
- 2-(2-(2-Chlorophenyl)acetyl)-N-(3-(trifluoromethyl)phenyl)hydrazine-1-carboxamide (CAS 497060-12-5)
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Recommended Standards
- 3-Bromo-4-chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 920966-51-4)
- 1-(Benzenesulfonyl)-5-bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine (CAS 876343-81-6)
- 1-(Benzenesulfonyl)-3-bromo-6-chloro-1H-pyrrolo[2,3-b]pyridine (CAS 1638761-42-8)
- 5-chloro-3-iodo-1-(oxan-2-yl)-1H-pyrazolo[4,3-b]pyridine (CAS 1416713-15-9)
- (S)-2-((tert-butoxycarbonyl)amino)-3-(2'-methoxy-[1,1'-biphenyl]-4-yl)propanoic acid (CAS 154116-45-7)
- 1-(Phenyl(o-tolyl)methyl)piperazine (CAS 24342-61-8)
- N2,2-Dimethyl-1,2-propanediamine (CAS 116577-09-4)
- Ceftriaxone Sodium - Impurity E (Sodium Salt) (CAS 2227256-62-2)
- Methyl 4-ethyl-6,7-dihydro-1H-imidazo[4,5-c]pyridine-5(4H)-carboxylate (CAS 424837-44-5)
- Triisopropylsilanol (CAS 17877-23-5)
- 3,3-Dimethyl-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine (CAS 1823891-04-8)
- 7-Boc-1,7-diazaspiro[3.5]nonan-2-one (CAS 392331-78-1)
- Trichloronate (CAS 327-98-0)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
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