5-(4-Chlorophenyl)-2-{[(4-fluorophenyl)methyl]sulfanyl}pyrimidine CAS 344281-72-7
| CAS No. | 344281-72-7 |
| Molecular Formula | C17H12ClFN2S |
| Molecular Weight | 330.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(4-Chlorophenyl)-2-{[(4-fluorophenyl)methyl]sulfanyl}pyrimidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-(4-Chlorophenyl)-2-{[(4-fluorophenyl)methyl]sulfanyl}pyrimidine (CAS 344281-72-7) is a high-purity analytical reference standard with the molecular formula C17H12ClFN2S and a molecular weight of 330.81 g/mol.
5-(4-Chlorophenyl)-2-{[(4-fluorophenyl)methyl]sulfanyl}pyrimidine (C17H12ClFN2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(4-Chlorophenyl)-2-{[(4-fluorophenyl)methyl]sulfanyl}pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H12ClFN2S |
| Molecular Weight | 330.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 2-(2-Chlorophenyl)-4,5-diphenyl-1h-imidazole (CAS 1707-67-1)
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- 2-(4-Chlorophenyl)-4,5-diphenyl-1H-imidazole (CAS 5496-32-2)
- 4-((4-Chlorophenyl)sulfonyl)-3-methylthiophene-2-carbohydrazide (CAS 845266-19-5)
- 4-(4-Chlorophenyl)-2-(4-isopropylphenyl)-4-oxobutanoic acid (CAS 344281-36-3)
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- N-(4-chlorophenyl)-2-(4-(pyridin-2-yl)piperazin-1-yl)acetamide (CAS 303091-90-9)
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Recommended Standards
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