ROX NHS ester, 5-isomer CAS 344402-35-3
| CAS No. | 344402-35-3 |
| Molecular Formula | C37H33N3O7 |
| Molecular Weight | 631.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
ROX NHS ester, 5-isomer (CAS 344402-35-3), molecular formula C37H33N3O7 and molecular weight 631.67 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, ROX NHS ester, 5-isomer (C37H33N3O7) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 23.0, corresponding to approximately 23 ring(s) or double-bond equivalent(s). With a molecular weight of 631.67 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C37H33N3O7 |
| Molecular Weight | 631.67 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 23.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Recommended Standards
- Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc (CAS 2435720-04-8)
- Gliadins (CAS 9007-90-3)
- 6-Carboxy-X-rhodamine, succinimidyl ester (CAS 216699-36-4)
- DPP26-CHO-Br (CAS 1858204-07-5)
- 2-(3-Bromophenyl)-5-cyclopropyl-1,3,4-oxadiazole (CAS 39959-43-8)
- Methyl 4-bromo-5-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazole-3-carboxylate (CAS 2641466-07-9)
- rac-(1R,2S)-2-methoxycyclopentane-1-sulfonyl chloride (CAS 1909286-57-2)
- 1,3-Benzenedicarboxylic acid, polymer with 1,3-butanediol and hexanedioic acid, isodecyl ester (CAS 81603-78-3)
- 3-(Benzo[d][1,3]dioxol-5-yl)propan-1-ol (CAS 7031-03-0)
- 5-Chloro-4H-1,2,4-triazole-3-carboxamide (CAS 54671-66-8)
- DL-2,5-Dimethoxy-4-iodoamphetamine hydrochloride (CAS 42203-78-1)
- Methyl 6-chloro-3-ethoxy-2-fluorobenzoate (CAS 2385337-05-1)
- 2-Amino-1-(3-chlorophenyl)ethanol (CAS 53360-89-7)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com