1-(2-Fluoro-4-methoxyphenyl)propan-1-one CAS 344408-55-5
| CAS No. | 344408-55-5 |
| Molecular Formula | C10H11FO2 |
| Molecular Weight | 182.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(2-Fluoro-4-methoxyphenyl)propan-1-one (CAS 344408-55-5) is a high-purity analytical reference standard with the molecular formula C10H11FO2 and a molecular weight of 182.19 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 1-(2-Fluoro-4-methoxyphenyl)propan-1-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 182.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11FO2 |
| Molecular Weight | 182.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Fluoro Standards
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- 1-(5-Fluoro-2-methoxyphenyl)propan-2-one (CAS 1017082-10-8)
- 3-(3-Fluoro-5-methylphenyl)propanoic acid (CAS 1017779-56-4)
- 3-Fluoro-4-(propan-2-yloxy)benzaldehyde (CAS 1021231-72-0)
- 3-(3-fluoro-4-methoxyphenyl)propanal (CAS 1036396-31-2)
- 3-Fluoro-2-isopropoxybenzaldehyde (CAS 1037092-98-0)
- Ethyl 3-Fluoro-2-methylbenzoate (CAS 114312-57-1)
- 2-(3-Fluoro-4-methoxyphenyl)-2-methyloxirane (CAS 1189785-35-0)
Recommended Standards
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- 1-(2,2,2-trifluoroethyl)-1,4-diazepane (CAS 926216-03-7)
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- 2-(dimethylamino)-2-(1-methyl-1H-imidazol-5-yl)acetic acid dihydrochloride (CAS 1803562-91-5)
- 1-(7-Bromo-2,3-dihydro-1H-inden-5-yl)ethan-1-one (CAS 810680-94-5)
- 2-(4-Chlorobenzenesulfinyl)-4,6-dimethyl-3-(4-methylbenzenesulfonyl)pyridine (CAS 477762-79-1)
- 4-Oxo-4,6,7,8,9,10-hexahydropyrido[1,2-a]azepine-1-carboxylic acid (CAS 1515186-97-6)
- Sikokianin A (CAS 106293-99-6)
- (4AR,6S,7R,8S,8aS)-8-(allyloxy)-7-(benzyloxy)-6-(4-methoxyphenoxy)-2-phenylhexahydropyrano[3,2-d][1,3]dioxine (CAS 2160551-35-7)
- 6-(4-Methoxyphenyl)-5-methyl-3-(pyridin-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 685109-46-0)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
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