1-(Benzo[d][1,3]dioxol-5-yl)-3-(4-(4-fluorophenyl)piperazin-1-yl)propan-1-one CAS 344569-55-7
| CAS No. | 344569-55-7 |
| Molecular Formula | C20H21FN2O3 |
| Molecular Weight | 356.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 356.39 g/mol gives 1-(Benzo[d][1,3]dioxol-5-yl)-3-(4-(4-fluorophenyl)piperazin-1-yl)propan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-(Benzo[d][1,3]dioxol-5-yl)-3-(4-(4-fluorophenyl)piperazin-1-yl)propan-1-one (CAS 344569-55-7), a certified reference material (molecular formula C20H21FN2O3, MW 356.39 g/mol) for analytical method development and quality control.
The molecular framework of 1-(Benzo[d][1,3]dioxol-5-yl)-3-(4-(4-fluorophenyl)piperazin-1-yl)propan-1-one (C20H21FN2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(Benzo[d][1,3]dioxol-5-yl)-3-(4-(4-fluorophenyl)piperazin-1-yl)propan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H21FN2O3 |
| Molecular Weight | 356.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Benzo Standards
- 4-((3-(Benzo[d][1,3]dioxol-5-yloxy)propyl)sulfonyl)piperazine-1-carbaldehyde (CAS 946286-38-0)
- N-(Benzo[d][1,3]dioxol-5-yl)-2-((6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)oxy)acetamide (CAS 1030097-27-8)
- Ethyl 4-(2-(benzo[d]oxazol-2-ylthio)acetamido)benzoate (CAS 58915-09-6)
- 1-((1-(Benzo[d]oxazol-2-yl)piperidin-4-yl)methyl)-3-(thiophen-2-yl)urea (CAS 1797285-75-6)
- 4-((4-(1H-Benzo[d]imidazol-2-yl)piperidin-1-yl)sulfonyl)aniline (CAS 951921-21-4)
- 5,5'-(Benzo[c][1,2,5]thiadiazole-4,7-diyl)bis(thiophene-2-carbaldehyde) (CAS 882303-63-1)
- 1-(Benzo[d][1,3]dioxol-5-yl)-2-((4-methyl-6-(trifluoromethyl)pyrimidin-2-yl)thio)ethan-1-one (CAS 940984-29-2)
- Rel-2-(benzo[b]thiophen-4-yl)-N-methyl-N-((1R,2R)-2-(pyrrolidin-1-yl)cyclohexyl)acetamide (CAS 111728-01-9)
Recommended Standards
- (2Z)-3-[(3,5-Dimethoxyphenyl)amino]-2-[4-(3-fluoropropoxy)phenyl]prop-2-enenitrile (CAS 478039-54-2)
- 1,6-Anhydro-3,4-O-isopropylidene-2-tosyl-β-D-galactopyranose (CAS 81028-98-0)
- (1-((4-Methoxyphenyl)sulfonyl)piperidine-3-carbonyl)glycine (CAS 919733-29-2)
- 1'-[5-(Trifluoromethyl)pyridin-2-yl]-[1,4'-bipiperidine]-4'-carboxamide (CAS 551931-39-6)
- 5-Bromo-2-ethyl-3,4-dihydropyrimidin-4-one (CAS 1528580-99-5)
- (2R)-2-amino-3-(1-methylcyclobutyl)propanoic acid (CAS 1841099-11-3)
- 2,5-Diacetamidotoluene (CAS 19039-27-1)
- Gadoteridol Impurity 2 (CAS CATO-C4X-22572)
- 4-Fluoro-1,5-dimethyl-1H-indole (CAS 1936314-07-6)
- 5-CHloro-n-(furan-2-ylmethyl)pyrimidin-2-amine (CAS 1526836-87-2)
- N-(2,6-dimethylphenyl)-N-(methylsulfonyl)glycine (CAS 312275-42-6)
- N-(2-Methylallyl)-2,3-dihydrobenzofuran-6-amine (CAS 61070-35-7)
- tert-Butyl 4-hydroxy-2-phenylbutan-2-ylcarbamate (CAS 1255574-56-1)
- Tetrapeptide-3 (CAS 827306-97-8)
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