2-Cyclopropyl-5-(3-(trifluoromethyl)phenyl)-1H-imidazole CAS 345589-49-3
| CAS No. | 345589-49-3 |
| Molecular Formula | C13H11F3N2 |
| Molecular Weight | 252.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Cyclopropyl-5-(3-(trifluoromethyl)phenyl)-1H-imidazole (C13H11F3N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2-Cyclopropyl-5-(3-(trifluoromethyl)phenyl)-1H-imidazole (CAS 345589-49-3), molecular formula C13H11F3N2 and molecular weight 252.24 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Cyclopropyl-5-(3-(trifluoromethyl)phenyl)-1H-imidazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H11F3N2 |
| Molecular Weight | 252.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Cyclopropyl Standards
- 4-Cyclopropyl-1-phenyl-1,6-dihydro-7H-pyrazolo[3,4-d]pyridazin-7-one (CAS 1105197-41-8)
- N-Cyclopropyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine (CAS 551919-54-1)
- n-Cyclopropyl-4-(3,4-difluorophenyl)thiazol-2-amine (CAS 923771-78-2)
- 2-(7-Cyclopropyl-5-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-3-yl)acetic acid (CAS 1411766-66-9)
- Cyclopropyl({4'-methoxy-[1,1'-biphenyl]-4-yl})methanone (CAS 865659-55-8)
- 2-((Cyclopropyl(thiophen-2-yl)methyl)amino)-N-isopropylacetamide (CAS 1274523-10-2)
- 2-Cyclopropyl-5-(iodomethyl)oxolane (CAS 1849210-29-2)
- 2-Cyclopropyl-5-iodo-1,3,4-thiadiazole (CAS 1260220-03-8)
Recommended Standards
- 2-(4-Fluorophenyl)-5,8-dioxaspiro[3.4]Octane-2-carboxylic acid (CAS 2168835-29-6)
- 4-(5-Formylfuran-2-yl)benzenesulfonic acid (CAS 68502-11-4)
- [3-(4-Fluorobenzyl)-2-oxoimidazolidin-1-yl]acetic acid (CAS 897769-22-1)
- 5-(4-Fluorobenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 876405-68-4)
- 7-Bromo-5-methyl-2,3-dihydro-1-benzofuran-3-one (CAS 1153450-24-8)
- 3-tert-Butyl-1-methyl-1h-pyrazole-4-carboxylic acid (CAS 1152548-57-6)
- (7R,8aS)-7-Aminohexahydropyrrolo[1,2-a]pyrazine-1,4-dione (CAS 1256636-25-5)
- Sodium acetylacetonate hydrate, min. 98% (CAS 15435-71-9)
- (3R,4S)-3-Fluoro-N,N-dimethylpiperidin-4-amine dihydrochloride (CAS 2306254-53-3)
- 1-(3,4-Difluorophenyl)pentan-1-one (CAS 1094374-82-9)
- N,N'-([4,4'-Bithiazole]-2,2'-diyl)dicyclohexanecarboxamide (CAS 393838-72-7)
- 1-(4-(1H-Indol-1-yl)phenyl)ethanone (CAS 25700-07-6)
- 3-Bromo-8-(trifluoromethoxy)quinoline (CAS 2241594-65-8)
- 69558-55-0 O3Y80ZF13F Thymopentin Thymopentin [USAN:INN:BAN] L-Tyrosine, N-(N-(N-(N2-L-arginyl-L-lysyl)-L-alpha-aspartyl)-L-valyl)- L-Tyrosine, N-(N-(N-(N(sup 2)-L-arginyl-L-lysyl)-L-alpha-aspartyl)-L-valyl)- Thymopentine [French] Thymopentinum [Latin] Timopentina [Spanish] Thymopoietin 32-36 TP-5 Thymopoietin pentapeptide ORF-15244 Thymopentine Thymopentinum Timopentina ORF 15244 UNII-O3Y80ZF13F (CAS 69558-55-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com