4-Chloro-2,3-dioxoindoline-5-sulfonamide CAS 3456-81-3
| CAS No. | 3456-81-3 |
| Molecular Formula | C8H5ClN2O4S |
| Molecular Weight | 260.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-2,3-dioxoindoline-5-sulfonamide.
4-Chloro-2,3-dioxoindoline-5-sulfonamide (CAS 3456-81-3), molecular formula C8H5ClN2O4S and molecular weight 260.65 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 4-Chloro-2,3-dioxoindoline-5-sulfonamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 260.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-2,3-dioxoindoline-5-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2O4S |
| Molecular Weight | 260.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-5-sulfamoylphthalimide (CAS 3861-99-2)
- 2-Chloro-N-(2-(dimethylamino)-2-oxoethyl)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1178506-83-6)
- 3-Chloro-1-(trifluoromethyl)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile (CAS 1279214-67-3)
- 5-Chloro-2-(1H-pyrrol-1-yl)-4-(trifluoromethyl)aniline (CAS 1315619-16-9)
- 4-Chloro-5-[3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl]pyrimidine (CAS 1370598-55-2)
- 2-Chloro-6-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 1496260-94-6)
- Ethyl 2-[(5-chloro-3-nitropyridin-2-yl)oxy]acetate (CAS 105544-27-2)
- Ethyl 4-chloro-6-methoxy-5-nitronicotinate (CAS 1210835-76-9)
Recommended Standards
- 2,4-Dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonyl chloride (CAS 56044-12-3)
- 1H-Pyrazolo[4,3-d]pyrimidine, 5-chloro-3-fluoro-7-methoxy-1-(2-methoxyethyl)- (CAS 2445848-22-4)
- 6-Nitro-1H-indole-3-sulfonyl chloride (CAS 132745-00-7)
- 1-(Difluoromethyl)-3-(methoxymethyl)-1H-pyrazole-4-sulfonyl chloride (CAS 1856050-89-9)
- (S)-2-Amino-3-(benzhydrylthio)propanoic acid (CAS 247595-31-9)
- p-(Methylthio)benzyl thiocyanate (CAS 19927-29-8)
- 3-(1-(4-Bromophenyl)-1H-pyrrol-2-yl)-3-oxopropanenitrile (CAS 1403564-15-7)
- Linezolid Impurity 28 (CAS CATO-C4X-107328)
- 2-Bromo-3-chloro-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one (CAS 2766230-77-5)
- 1-(2-Ethyl-1-(1-methoxypropan-2-yl)-1H-imidazol-5-yl)ethanone (CAS 600699-63-6)
- 2-Ethoxy-N-((1-(hydroxymethyl)cyclopropyl)methyl)-1-naphthamide (CAS 1257553-53-9)
- 6-Bromo-2,4-fifluoro-3-formylphenylboronic acid pinacol ester (CAS 2121512-44-3)
- 3-(2-(1H-indol-3-yl)oxazol-4-yl)propan-1-amine hydrochloride (CAS 2448337-79-7)
- Semaglutide impurity 272 (CAS CATO-C4X-2226272)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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