Ethyl 1,3-dioxo-2,3-dihydro-1H-indene-2-carboxylate CAS 3457-77-0
| CAS No. | 3457-77-0 |
| Molecular Formula | C12H10O4 |
| Molecular Weight | 218.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Ethyl 1,3-dioxo-2,3-dihydro-1H-indene-2-carboxylate (CAS 3457-77-0), molecular formula C12H10O4 and molecular weight 218.21 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 1,3-dioxo-2,3-dihydro-1H-indene-2-carboxylate (C12H10O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Ethyl 1,3-dioxo-2,3-dihydro-1H-indene-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10O4 |
| Molecular Weight | 218.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Ethyl Standards
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Recommended Standards
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- 1,3-Dimethyl-2-oxo-1,2-dihydroquinoxaline-6-carboxylic acid (CAS 1132638-95-9)
- 5-Ethyl 2-methyl pyridine-2,5-dicarboxylate (CAS 110911-08-5)
- Methyl 2-(2-hydroxyphenyl)propanoate (CAS 54493-89-9)
- 4-Ethyl-5-(5-nitrofuran-2-yl)-4H-1,2,4-triazol-3-amine (CAS 41735-52-8)
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